ENSG00000174564


Homo sapiens

Features
Gene ID: ENSG00000174564
  
Biological name :IL20RB
  
Synonyms : IL20RB / interleukin 20 receptor subunit beta / Q6UXL0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.3
Gene start: 136946230
Gene end: 137011085
  
Corresponding Affymetrix probe sets: 204725_s_at (Human Genome U133 Plus 2.0 Array)   228575_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000328133
Ensembl peptide - ENSP00000417437
Ensembl peptide - ENSP00000418637
Ensembl peptide - ENSP00000420725
NCBI entrez gene - 53833     See in Manteia.
OMIM - 605621
RefSeq - XM_017006632
RefSeq - NM_144717
RefSeq - XM_006713665
RefSeq - XM_011512910
RefSeq - XM_011512911
RefSeq Peptide - NP_653318
swissprot - Q6UXL0
swissprot - F8WC67
swissprot - H7C5S5
swissprot - F8WAV8
Ensembl - ENSG00000174564
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crfb16ENSDARG00000075181Danio rerio
 IL20RBENSGALG00000013169Gallus gallus
 Il20rbENSMUSG00000044244Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015373  Interferon/interleukin receptor domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001808 negative regulation of type IV hypersensitivity IEA
 biological_processGO:0002437 inflammatory response to antigenic stimulus IEA
 biological_processGO:0002765 immune response-inhibiting signal transduction IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0032689 negative regulation of interferon-gamma production IEA
 biological_processGO:0032703 negative regulation of interleukin-2 production IEA
 biological_processGO:0032733 positive regulation of interleukin-10 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050863 regulation of T cell activation IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004920 interleukin-10 receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042015 interleukin-20 binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000162892 IL24 / Q13007 / interleukin 24  / complex
 ENSG00000142677 Q8N6P7 / IL22RA1 / interleukin 22 receptor subunit alpha 1  / complex
 ENSG00000142224 IL19 / Q9UHD0 / interleukin 19  / complex
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex
 ENSG00000016402 IL20RA / Q9UHF4 / interleukin 20 receptor subunit alpha  / complex
 ENSG00000115415 STAT1 / P42224 / signal transducer and activator of transcription 1  / complex
 ENSG00000162891 IL20 / Q9NYY1 / interleukin 20  / complex






 

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