ENSG00000162891


Homo sapiens

Features
Gene ID: ENSG00000162891
  
Biological name :IL20
  
Synonyms : IL20 / interleukin 20 / Q9NYY1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 206865354
Gene end: 206869223
  
Corresponding Affymetrix probe sets: 224071_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356065
Ensembl peptide - ENSP00000375796
Ensembl peptide - ENSP00000356063
NCBI entrez gene - 50604     See in Manteia.
OMIM - 605619
RefSeq - NM_018724
RefSeq - XM_005273152
RefSeq Peptide - NP_061194
swissprot - Q9NYY1
Ensembl - ENSG00000162891
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il19lENSDARG00000090344Danio rerio
 Il20ENSMUSG00000026416Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL19 / Q9UHD0 / interleukin 19ENSG0000014222440
IL24 / Q13007 / interleukin 24ENSG0000016289230


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020423  Interleukin-10, conserved site
 IPR020442  Interleukin-20
 IPR020443  Interleukin-10/19/20/22/24/26 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein TAS
 biological_processGO:0045606 positive regulation of epidermal cell differentiation TAS
 biological_processGO:0045618 positive regulation of keratinocyte differentiation TAS
 biological_processGO:0045672 positive regulation of osteoclast differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0045517 interleukin-20 receptor binding TAS
 molecular_functionGO:0045518 interleukin-22 receptor binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000174564 IL20RB / Q6UXL0 / interleukin 20 receptor subunit beta  / complex
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex
 ENSG00000016402 IL20RA / Q9UHF4 / interleukin 20 receptor subunit alpha  / complex
 ENSG00000142677 Q8N6P7 / IL22RA1 / interleukin 22 receptor subunit alpha 1  / complex






 

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