ENSG00000142224


Homo sapiens

Features
Gene ID: ENSG00000142224
  
Biological name :IL19
  
Synonyms : IL19 / interleukin 19 / Q9UHD0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 206798870
Gene end: 206842981
  
Corresponding Affymetrix probe sets: 220745_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000270218
Ensembl peptide - ENSP00000343000
Ensembl peptide - ENSP00000482668
NCBI entrez gene - 29949     See in Manteia.
OMIM - 605687
RefSeq - NM_013371
RefSeq - NM_153758
RefSeq Peptide - NP_037503
RefSeq Peptide - NP_715639
swissprot - Q9UHD0
Ensembl - ENSG00000142224
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il19lENSDARG00000090344Danio rerio
 IL19ENSGALG00000000911Gallus gallus
 Il19ENSMUSG00000016524Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL20 / Q9NYY1 / interleukin 20ENSG0000016289133
IL24 / Q13007 / interleukin 24ENSG0000016289223


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020421  Interleukin-19
 IPR020423  Interleukin-10, conserved site
 IPR020443  Interleukin-10/19/20/22/24/26 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006955 immune response NAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0042226 interleukin-6 biosynthetic process IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity TAS


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000016402 IL20RA / Q9UHF4 / interleukin 20 receptor subunit alpha  / complex
 ENSG00000174564 IL20RB / Q6UXL0 / interleukin 20 receptor subunit beta  / complex
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex






 

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