ENSG00000162892


Homo sapiens

Features
Gene ID: ENSG00000162892
  
Biological name :IL24
  
Synonyms : IL24 / interleukin 24 / Q13007
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 206897443
Gene end: 206904139
  
Corresponding Affymetrix probe sets: 206569_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375795
Ensembl peptide - ENSP00000356062
Ensembl peptide - ENSP00000418933
Ensembl peptide - ENSP00000484900
Ensembl peptide - ENSP00000294984
Ensembl peptide - ENSP00000356060
NCBI entrez gene - 11009     See in Manteia.
OMIM - 604136
RefSeq - XM_017000121
RefSeq - NM_001185156
RefSeq - NM_001185157
RefSeq - NM_001185158
RefSeq - NM_006850
RefSeq - XM_011509101
RefSeq Peptide - NP_001172087
RefSeq Peptide - NP_001172086
RefSeq Peptide - NP_001172085
RefSeq Peptide - NP_006841
swissprot - E7ER64
swissprot - E7ETP6
swissprot - Q13007
Ensembl - ENSG00000162892
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il19lENSDARG00000090344Danio rerio
 Il24ENSMUSG00000026420Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL20 / Q9NYY1 / interleukin 20ENSG0000016289126
IL19 / Q9UHD0 / interleukin 19ENSG0000014222424


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020423  Interleukin-10, conserved site
 IPR020444  Interleukin-24


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042501 serine phosphorylation of STAT protein IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex
 ENSG00000016402 IL20RA / Q9UHF4 / interleukin 20 receptor subunit alpha  / complex
 ENSG00000142677 Q8N6P7 / IL22RA1 / interleukin 22 receptor subunit alpha 1  / complex
 ENSG00000174564 IL20RB / Q6UXL0 / interleukin 20 receptor subunit beta  / complex
 ENSG00000115415 STAT1 / P42224 / signal transducer and activator of transcription 1  / complex






 

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