ENSMUSG00000026416


Mus musculus

Features
Gene ID: ENSMUSG00000026416
  
Biological name :Il20
  
Synonyms : Il20 / interleukin 20 / Q9JKV9
  
Possible biological names infered from orthology : Q9NYY1
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 130906985
Gene end: 130911451
  
Corresponding Affymetrix probe sets: 10357562 (MoGene1.0st)   1421608_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027673
Ensembl peptide - ENSMUSP00000141088
NCBI entrez gene - 58181     See in Manteia.
MGI - MGI:1890473
RefSeq - NM_021380
RefSeq - NM_001311091
RefSeq Peptide - NP_001298020
RefSeq Peptide - NP_067355
swissprot - Q2NKI0
swissprot - Q2THG5
swissprot - Q9JKV9
Ensembl - ENSMUSG00000026416
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il19lENSDARG00000090344Danio rerio
 IL20ENSG00000162891Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Il19 / Q8CJ70 / Interleukin-19 / Q9UHD0*ENSMUSG0000001652436
Il24 / interleukin 24 / Q13007*ENSMUSG0000002642030


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR020423  Interleukin-10, conserved site
 IPR020442  Interleukin-20
 IPR020443  Interleukin-10/19/20/22/24/26 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030097 hemopoiesis NAS
 biological_processGO:0045672 positive regulation of osteoclast differentiation IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005125 cytokine activity ISS
 molecular_functionGO:0045517 interleukin-20 receptor binding IPI
 molecular_functionGO:0045518 interleukin-22 receptor binding IPI


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002534 type IV hypersensitivity reaction "an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact " [Pathology , 2nd edition:ISBN 0-397-51047-0]
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Allelic Composition: Bhlha15tm3(cre/ERT2)Skz/Bhlha15tm3(cre/ERT2)Skz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020007 Il20ra / Q6PHB0 / interleukin 20 receptor, alpha / Q9UHF4* / interleukin 20 receptor subunit alpha*  / complex
 ENSMUSG00000028530 Jak1 / Janus kinase 1 / P23458*  / complex
 ENSMUSG00000004040 Stat3 / P42227 / Signal transducer and activator of transcription 3 / P40763*  / complex
 ENSMUSG00000037157 Q80XZ4 / Il22ra1 / Interleukin-22 receptor subunit alpha-1 / Q8N6P7*  / complex
 ENSMUSG00000044244 Il20rb / interleukin 20 receptor subunit beta / Q6UXL0*  / complex






 

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