ENSG00000164938


Homo sapiens

Features
Gene ID: ENSG00000164938
  
Biological name :TP53INP1
  
Synonyms : Q96A56 / TP53INP1 / tumor protein p53 inducible nuclear protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q22.1
Gene start: 94925972
Gene end: 94949411
  
Corresponding Affymetrix probe sets: 225912_at (Human Genome U133 Plus 2.0 Array)   235602_at (Human Genome U133 Plus 2.0 Array)   244721_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390063
Ensembl peptide - ENSP00000344215
NCBI entrez gene - 94241     See in Manteia.
OMIM - 606185
RefSeq - XM_011517386
RefSeq - NM_001135733
RefSeq - NM_033285
RefSeq Peptide - NP_001129205
RefSeq Peptide - NP_150601
swissprot - Q96A56
swissprot - A0A024R9C8
Ensembl - ENSG00000164938
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tp53inp1ENSDARG00000028017Danio rerio
 TP53INP1ENSGALG00000041353Gallus gallus
 Q9QXE4ENSMUSG00000028211Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IXH6 / TP53INP2 / tumor protein p53 inducible nuclear protein 2ENSG0000007880428


Protein motifs (from Interpro)
Interpro ID Name
 IPR029431  Tumour protein p53-inducible nuclear protein
 IPR029556  Tumor protein p53-inducible nuclear protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0048102 autophagic cell death IMP
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0071361 cellular response to ethanol IEA
 biological_processGO:0071447 cellular response to hydroperoxide IEA
 biological_processGO:0072703 cellular response to methyl methanesulfonate IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:1904761 negative regulation of myofibroblast differentiation IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016209 antioxidant activity ISS


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Regulation of TP53 Activity through Phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000127445 PIN1 / Q13526 / peptidylprolyl cis/trans isomerase, NIMA-interacting 1  / reaction / complex
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction
 ENSG00000064393 HIPK2 / Q9H2X6 / homeodomain interacting protein kinase 2  / complex / reaction






 

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