ENSG00000165879


Homo sapiens

Features
Gene ID: ENSG00000165879
  
Biological name :FRAT1
  
Synonyms : FRAT1 / FRAT1, WNT signaling pathway regulator / Q92837
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.1
Gene start: 97319267
Gene end: 97321915
  
Corresponding Affymetrix probe sets: 219889_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360060
NCBI entrez gene - 10023     See in Manteia.
OMIM - 602503
RefSeq - NM_005479
RefSeq Peptide - NP_005470
swissprot - Q92837
Ensembl - ENSG00000165879
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Frat1ENSMUSG00000067199Mus musculus
 Peg12ENSMUSG00000070526Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FRAT2 / O75474 / FRAT2, WNT signaling pathway regulatorENSG0000018127466


Protein motifs (from Interpro)
Interpro ID Name
 IPR008014  Glycogen synthase kinase-3 binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:1904886 beta-catenin destruction complex disassembly TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000082701 GSK3B / P49841 / glycogen synthase kinase 3 beta  / reaction / complex






 

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