ENSG00000165912


Homo sapiens

Features
Gene ID: ENSG00000165912
  
Biological name :PACSIN3
  
Synonyms : PACSIN3 / protein kinase C and casein kinase substrate in neurons 3 / Q9UKS6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p11.2
Gene start: 47177525
Gene end: 47186443
  
Corresponding Affymetrix probe sets: 218744_s_at (Human Genome U133 Plus 2.0 Array)   235734_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431924
Ensembl peptide - ENSP00000440945
Ensembl peptide - ENSP00000437252
Ensembl peptide - ENSP00000435672
Ensembl peptide - ENSP00000435638
Ensembl peptide - ENSP00000434699
Ensembl peptide - ENSP00000434521
Ensembl peptide - ENSP00000433962
Ensembl peptide - ENSP00000431948
Ensembl peptide - ENSP00000298838
Ensembl peptide - ENSP00000431861
NCBI entrez gene - 29763     See in Manteia.
OMIM - 606513
RefSeq - NM_001184975
RefSeq - NM_016223
RefSeq - NM_001184974
RefSeq Peptide - NP_001171903
RefSeq Peptide - NP_001171904
RefSeq Peptide - NP_057307
swissprot - H0YDM6
swissprot - E9PQ12
swissprot - Q9UKS6
swissprot - E9PNM9
swissprot - E9PJ75
swissprot - E9PJ33
swissprot - E9PIZ6
swissprot - E9PIY1
swissprot - A0A0C4DGG1
Ensembl - ENSG00000165912
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pacsin3ENSDARG00000099339Danio rerio
 PACSIN3ENSGALG00000008231Gallus gallus
 Q99JB8ENSMUSG00000027257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UNF0 / PACSIN2 / protein kinase C and casein kinase substrate in neurons 2ENSG0000010026656
Q9BY11 / PACSIN1 / protein kinase C and casein kinase substrate in neurons 1ENSG0000012450751


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR028523  Protein kinase C and casein kinase substrate in neurons protein 3
 IPR031160  F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0045806 negative regulation of endocytosis IEA
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis IMP
 biological_processGO:0051926 negative regulation of calcium ion transport IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0097320 plasma membrane tubulation IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165912 Q9UKS6 / PACSIN3 / protein kinase C and casein kinase substrate in neurons 3  / complex






 

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