ENSG00000165934


Homo sapiens

Features
Gene ID: ENSG00000165934
  
Biological name :CPSF2
  
Synonyms : cleavage and polyadenylation specific factor 2 / CPSF2 / Q9P2I0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.12
Gene start: 92121937
Gene end: 92172145
  
Corresponding Affymetrix probe sets: 225986_x_at (Human Genome U133 Plus 2.0 Array)   225994_at (Human Genome U133 Plus 2.0 Array)   233208_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452503
Ensembl peptide - ENSP00000451390
Ensembl peptide - ENSP00000298875
Ensembl peptide - ENSP00000451418
NCBI entrez gene - 53981     See in Manteia.
OMIM - 606028
RefSeq - NM_017437
RefSeq - NM_001322270
RefSeq - NM_001322271
RefSeq - NM_001322272
RefSeq Peptide - NP_001309199
RefSeq Peptide - NP_059133
RefSeq Peptide - NP_001309201
RefSeq Peptide - NP_001309200
swissprot - Q9P2I0
swissprot - A0A024R6H0
swissprot - G3V3T7
swissprot - G3V5T3
swissprot - H0YJF4
Ensembl - ENSG00000165934
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpsf2ENSDARG00000028971Danio rerio
 CPSF2ENSGALG00000010783Gallus gallus
 Cpsf2ENSMUSG00000041781Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001279  Metallo-beta-lactamase
 IPR011108  Zn-dependent metallo-hydrolase, RNA specificity domain
 IPR022712  Beta-Casp domain
 IPR025069  Cleavage and polyadenylation specificity factor 2, C-terminal
 IPR027075  Cleavage and polyadenylation specificity factor subunit 2
 IPR035639  CPSF2, metallo-hydrolase domain
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006378 mRNA polyadenylation IEA
 biological_processGO:0006379 mRNA cleavage IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006398 mRNA 3"-end processing by stem-loop binding and cleavage IDA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005847 mRNA cleavage and polyadenylation specificity factor complex IEA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr