ENSG00000166579


Homo sapiens

Features
Gene ID: ENSG00000166579
  
Biological name :NDEL1
  
Synonyms : NDEL1 / nudE neurodevelopment protein 1 like 1 / Q9GZM8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p13.1
Gene start: 8413131
Gene end: 8490411
  
Corresponding Affymetrix probe sets: 208093_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464441
Ensembl peptide - ENSP00000464154
Ensembl peptide - ENSP00000464634
Ensembl peptide - ENSP00000333982
Ensembl peptide - ENSP00000369364
Ensembl peptide - ENSP00000384963
Ensembl peptide - ENSP00000462052
Ensembl peptide - ENSP00000462458
Ensembl peptide - ENSP00000462759
Ensembl peptide - ENSP00000463351
Ensembl peptide - ENSP00000463430
Ensembl peptide - ENSP00000463492
NCBI entrez gene - 81565     See in Manteia.
OMIM - 607538
RefSeq - XM_017025188
RefSeq - NM_001025579
RefSeq - NM_001330129
RefSeq - NM_030808
RefSeq - XM_011524013
RefSeq - XM_017025183
RefSeq - XM_017025184
RefSeq - XM_017025185
RefSeq - XM_017025186
RefSeq - XM_017025187
RefSeq Peptide - NP_001020750
RefSeq Peptide - NP_001317058
RefSeq Peptide - NP_110435
swissprot - J3KRK9
swissprot - J3KSF2
swissprot - J3KT16
swissprot - J3QL31
swissprot - J3QL85
swissprot - J3QLD0
swissprot - J3QRD2
swissprot - J3QRZ1
swissprot - J3QSD2
swissprot - Q9GZM8
swissprot - A6NIZ0
Ensembl - ENSG00000166579
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndel1aENSDARG00000010953Danio rerio
 ndel1bENSDARG00000104225Danio rerio
 NDEL1ENSGALG00000001163Gallus gallus
 Ndel1ENSMUSG00000018736Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NDE1 / Q9NXR1 / nudE neurodevelopment protein 1ENSG0000007286454


Protein motifs (from Interpro)
Interpro ID Name
 IPR006964  NUDE domain
 IPR033493  Nuclear distribution protein nudE-like 1
 IPR033494  NUDE family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000132 establishment of mitotic spindle orientation IBA
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0001833 inner cell mass cell proliferation IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007020 microtubule nucleation IBA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007100 mitotic centrosome separation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008090 retrograde axonal transport IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0010975 regulation of neuron projection development IBA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021955 central nervous system neuron axonogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0032418 lysosome localization ISS
 biological_processGO:0033157 regulation of intracellular protein transport IMP
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0045773 positive regulation of axon extension IEA
 biological_processGO:0047496 vesicle transport along microtubule IBA
 biological_processGO:0048680 positive regulation of axon regeneration IEA
 biological_processGO:0051081 nuclear envelope disassembly IEA
 biological_processGO:0051303 establishment of chromosome localization IBA
 biological_processGO:0051642 centrosome localization IBA
 biological_processGO:0060052 neurofilament cytoskeleton organization IEA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:1900029 positive regulation of ruffle assembly ISS
 biological_processGO:1990138 neuron projection extension IEA
 biological_processGO:2000574 regulation of microtubule motor activity IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IBA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005875 microtubule associated complex IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0043203 axon hillock IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0060053 neurofilament cytoskeleton IEA
 cellular_componentGO:0090724 central region of growth cone IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043014 alpha-tubulin binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA
 molecular_functionGO:0070012 oligopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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