ENSG00000166681


Homo sapiens

Features
Gene ID: ENSG00000166681
  
Biological name :BEX3
  
Synonyms : BEX3 / brain expressed X-linked 3 / Q00994
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.2
Gene start: 103376340
Gene end: 103378077
  
Corresponding Affymetrix probe sets: 217963_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354843
Ensembl peptide - ENSP00000361717
Ensembl peptide - ENSP00000361718
Ensembl peptide - ENSP00000361728
NCBI entrez gene - 27018     See in Manteia.
OMIM - 300361
RefSeq - NM_014380
RefSeq - NM_001282674
RefSeq - NM_206915
RefSeq - NM_206917
RefSeq Peptide - NP_001269603
RefSeq Peptide - NP_055195
RefSeq Peptide - NP_996798
RefSeq Peptide - NP_996800
swissprot - Q00994
Ensembl - ENSG00000166681
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Bex3ENSMUSG00000046432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BEX5 / Q5H9J7 / brain expressed X-linked 5ENSG0000018451559
BEX4 / Q9NWD9 / brain expressed X-linked 4ENSG0000010240954


Protein motifs (from Interpro)
Interpro ID Name
 IPR007623  Brain-expressed X-linked protein
 IPR021156  Transcription elongation factor A-like/Brain expressed X-linked


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005123 death receptor binding IEA
 molecular_functionGO:0005163 nerve growth factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process TAS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NADE modulates death signalling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000064300 NGFR / P08138 / nerve growth factor receptor  / complex / reaction
 ENSG00000134259 NGF / P01138 / nerve growth factor  / reaction / complex
 ENSG00000108953 YWHAE / P62258 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon  / complex / reaction
 ENSG00000164305 CASP3 / P42574 / caspase 3  / reaction
 ENSG00000106144 CASP2 / P42575 / caspase 2  / reaction






 

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