ENSG00000166869


Homo sapiens

Features
Gene ID: ENSG00000166869
  
Biological name :CHP2
  
Synonyms : calcineurin like EF-hand protein 2 / CHP2 / O43745
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.2
Gene start: 23754627
Gene end: 23758951
  
Corresponding Affymetrix probe sets: 206149_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000300113
NCBI entrez gene - 63928     See in Manteia.
RefSeq - NM_022097
RefSeq Peptide - NP_071380
swissprot - O43745
Ensembl - ENSG00000166869
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chp2ENSDARG00000025788Danio rerio
 Chp2ENSMUSG00000030865Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHP1 / Q99653 / calcineurin like EF-hand protein 1ENSG0000018744660
P63098 / PPP3R1 / protein phosphatase 3 regulatory subunit B, alphaENSG0000022182330
PPP3R2 / Q96LZ3 / protein phosphatase 3 regulatory subunit B, betaENSG0000018838629
AC017083.3ENSG0000027339828
TESC / Q96BS2 / tescalcinENSG0000008899225


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010922 positive regulation of phosphatase activity IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042307 positive regulation of protein import into nucleus IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade IDA
 biological_processGO:0071277 cellular response to calcium ion IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr