ENSMUSG00000030865


Mus musculus

Features
Gene ID: ENSMUSG00000030865
  
Biological name :Chp2
  
Synonyms : Calcineurin B homologous protein 2 / Chp2 / Q9D869
  
Possible biological names infered from orthology : calcineurin like EF-hand protein 2 / O43745
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F2
Gene start: 122219496
Gene end: 122222824
  
Corresponding Affymetrix probe sets: 10557165 (MoGene1.0st)   1431130_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033152
NCBI entrez gene - 70261     See in Manteia.
MGI - MGI:1917511
RefSeq - NM_027363
RefSeq - XM_011241899
RefSeq Peptide - NP_081639
swissprot - Q9D869
Ensembl - ENSMUSG00000030865
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chp2ENSDARG00000025788Danio rerio
 CHP2ENSG00000166869Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chp1 / P61022 / Calcineurin B homologous protein 1 / Q99653* / calcineurin like EF-hand protein 1*ENSMUSG0000001407759
Ppp3r1 / Q63810 / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) / P63098* / protein phosphatase 3 regulatory subunit B, alpha*ENSMUSG0000003395331
Ppp3r2 / Q63811 / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) / Q96LZ3* / protein phosphatase 3 regulatory subunit B, beta*ENSMUSG0000002831029
Tesc / Q9JKL5 / tescalcin / Q96BS2*ENSMUSG0000002935928
Tescl / TESC* / Q96BS2* / tescalcin*ENSMUSG0000005582626


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006814 sodium ion transport ISO
 biological_processGO:0006885 regulation of pH ISO
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010922 positive regulation of phosphatase activity IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042307 positive regulation of protein import into nucleus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade IEA
 biological_processGO:0071277 cellular response to calcium ion IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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