ENSMUSG00000029359


Mus musculus

Features
Gene ID: ENSMUSG00000029359
  
Biological name :Tesc
  
Synonyms : Q9JKL5 / Tesc / tescalcin
  
Possible biological names infered from orthology : Q96BS2
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 118027743
Gene end: 118061878
  
Corresponding Affymetrix probe sets: 10524955 (MoGene1.0st)   1418743_a_at (Mouse Genome 430 2.0 Array)   1418744_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031304
Ensembl peptide - ENSMUSP00000138436
NCBI entrez gene - 57816     See in Manteia.
MGI - MGI:1930803
RefSeq - NM_021344
RefSeq Peptide - NP_067319
swissprot - D0EM46
swissprot - D0EM45
swissprot - Q9JKL5
Ensembl - ENSMUSG00000029359
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tescaENSDARG00000028346Danio rerio
 tescbENSDARG00000030839Danio rerio
 TESCENSGALG00000008206Gallus gallus
 TESCENSG00000088992Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tescl / TESC* / Q96BS2* / tescalcin*ENSMUSG0000005582657
Chp1 / P61022 / Calcineurin B homologous protein 1 / Q99653* / calcineurin like EF-hand protein 1*ENSMUSG0000001407730
Chp2 / Q9D869 / Calcineurin B homologous protein 2 / O43745* / calcineurin like EF-hand protein 2*ENSMUSG0000003086526
Ppp3r1 / Q63810 / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) / P63098* / protein phosphatase 3 regulatory subunit B, alpha*ENSMUSG0000003395324
Ppp3r2 / Q63811 / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) / Q96LZ3* / protein phosphatase 3 regulatory subunit B, beta*ENSMUSG0000002831021


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0006883 cellular sodium ion homeostasis ISO
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0008584 male gonad development IEP
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030219 megakaryocyte differentiation IEP
 biological_processGO:0030854 positive regulation of granulocyte differentiation ISS
 biological_processGO:0032417 positive regulation of sodium:proton antiporter activity ISS
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin ISO
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0045654 positive regulation of megakaryocyte differentiation ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0050821 protein stabilization ISS
 biological_processGO:0051604 protein maturation ISS
 biological_processGO:0071300 cellular response to retinoic acid ISO
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004860 protein kinase inhibitor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0019212 phosphatase inhibitor activity IDA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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