ENSG00000167641


Homo sapiens

Features
Gene ID: ENSG00000167641
  
Biological name :PPP1R14A
  
Synonyms : PPP1R14A / protein phosphatase 1 regulatory inhibitor subunit 14A / Q96A00
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 38251237
Gene end: 38256591
  
Corresponding Affymetrix probe sets: 227006_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465811
Ensembl peptide - ENSP00000466572
Ensembl peptide - ENSP00000301242
Ensembl peptide - ENSP00000301243
Ensembl peptide - ENSP00000465104
NCBI entrez gene - 94274     See in Manteia.
OMIM - 608153
RefSeq - NM_033256
RefSeq - NM_001243947
RefSeq Peptide - NP_001230876
RefSeq Peptide - NP_150281
swissprot - Q96A00
swissprot - K7EJB8
swissprot - K7EMN0
swissprot - A0A0B4J2A3
Ensembl - ENSG00000167641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r14aaENSDARG00000011239Danio rerio
 ppp1r14abENSDARG00000017710Danio rerio
 Q91VC7ENSMUSG00000037166Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TAE6 / PPP1R14C / protein phosphatase 1 regulatory inhibitor subunit 14CENSG0000019872933
Q96C90 / PPP1R14B / protein phosphatase 1 regulatory inhibitor subunit 14BENSG0000017345731
Q9NXH3 / PPP1R14D / protein phosphatase 1 regulatory inhibitor subunit 14DENSG0000016614324


Protein motifs (from Interpro)
Interpro ID Name
 IPR008025  CPI-17
 IPR036658  CPI-17 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042325 regulation of phosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PKNs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123143 PKN1 / Q16512 / protein kinase N1  / reaction
 ENSG00000077157 O60237 / PPP1R12B / protein phosphatase 1 regulatory subunit 12B  / reaction / complex
 ENSG00000058272 O14974 / PPP1R12A / protein phosphatase 1 regulatory subunit 12A  / complex / reaction
 ENSG00000213639 P62140 / PPP1CB / protein phosphatase 1 catalytic subunit beta  / reaction / complex






 

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