ENSG00000167701


Homo sapiens

Features
Gene ID: ENSG00000167701
  
Biological name :GPT
  
Synonyms : glutamic--pyruvic transaminase / GPT / P24298
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.3
Gene start: 144502973
Gene end: 144507174
  
Corresponding Affymetrix probe sets: 206709_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378408
Ensembl peptide - ENSP00000433586
NCBI entrez gene - 2875     See in Manteia.
OMIM - 138200
RefSeq - XM_011516993
RefSeq - NM_005309
RefSeq Peptide - NP_005300
swissprot - P24298
Ensembl - ENSG00000167701
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpt2lENSDARG00000019541Danio rerio
 si:ch211-217a12.1ENSDARG00000055642Danio rerio
 GptENSMUSG00000022546Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPT2 / Q8TD30 / glutamic--pyruvic transaminase 2ENSG0000016612366


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008652 cellular amino acid biosynthetic process TAS
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0042853 L-alanine catabolic process IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004021 L-alanine:2-oxoglutarate aminotransferase activity EXP
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167701 GPT / P24298 / glutamic--pyruvic transaminase  / complex






 

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