ENSMUSG00000022546


Mus musculus

Features
Gene ID: ENSMUSG00000022546
  
Biological name :Gpt
  
Synonyms : glutamic pyruvic transaminase, soluble / Gpt / Q8QZR5
  
Possible biological names infered from orthology : glutamic--pyruvic transaminase / P24298
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D3
Gene start: 76695716
Gene end: 76699686
  
Corresponding Affymetrix probe sets: 10424979 (MoGene1.0st)   1426502_s_at (Mouse Genome 430 2.0 Array)   1453216_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155686
Ensembl peptide - ENSMUSP00000023203
Ensembl peptide - ENSMUSP00000155475
Ensembl peptide - ENSMUSP00000155491
Ensembl peptide - ENSMUSP00000155553
NCBI entrez gene - 76282     See in Manteia.
MGI - MGI:95802
RefSeq - NM_182805
RefSeq Peptide - NP_877957
swissprot - Q566C3
swissprot - Q8QZR5
Ensembl - ENSMUSG00000022546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpt2lENSDARG00000019541Danio rerio
 si:ch211-217a12.1ENSDARG00000055642Danio rerio
 GPTENSG00000167701Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpt2 / Q8BGT5 / glutamic pyruvate transaminase (alanine aminotransferase) 2 / Q8TD30* / glutamic--pyruvic transaminase 2*ENSMUSG0000003170066


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0042853 L-alanine catabolic process IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004021 L-alanine:2-oxoglutarate aminotransferase activity ISO
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022546 Gpt / Q8QZR5 / glutamic pyruvic transaminase, soluble / P24298* / glutamic--pyruvic transaminase*  / complex






 

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