ENSG00000168350


Homo sapiens

Features
Gene ID: ENSG00000168350
  
Biological name :DEGS2
  
Synonyms : DEGS2 / delta 4-desaturase, sphingolipid 2 / Q6QHC5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.2
Gene start: 100143957
Gene end: 100160163
  
Corresponding Affymetrix probe sets: 236496_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307126
Ensembl peptide - ENSP00000450637
NCBI entrez gene - 123099     See in Manteia.
OMIM - 610862
RefSeq - XM_006720043
RefSeq - NM_206918
RefSeq Peptide - NP_996801
swissprot - Q6QHC5
swissprot - G3V2F9
Ensembl - ENSG00000168350
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 degs2ENSDARG00000042544Danio rerio
 DEGS2ENSGALG00000011213Gallus gallus
 Degs2ENSMUSG00000021263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DEGS1 / O15121 / delta 4-desaturase, sphingolipid 1ENSG0000014375363


Protein motifs (from Interpro)
Interpro ID Name
 IPR005804  Fatty acid desaturase domain
 IPR011388  Sphingolipid delta4-desaturase
 IPR013866  Sphingolipid delta4-desaturase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006667 sphinganine metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000170 sphingosine hydroxylase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042284 sphingolipid delta-4 desaturase activity IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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