ENSMUSG00000021263


Mus musculus

Features
Gene ID: ENSMUSG00000021263
  
Biological name :Degs2
  
Synonyms : Degs2 / Q8R2F2 / Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
  
Possible biological names infered from orthology : delta 4-desaturase, sphingolipid 2 / Q6QHC5
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 108678711
Gene end: 108702315
  
Corresponding Affymetrix probe sets: 10402575 (MoGene1.0st)   1424549_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152122
Ensembl peptide - ENSMUSP00000021691
Ensembl peptide - ENSMUSP00000125891
NCBI entrez gene - 70059     See in Manteia.
MGI - MGI:1917309
RefSeq - NM_001171002
RefSeq - NM_027299
RefSeq Peptide - NP_001164473
RefSeq Peptide - NP_081575
swissprot - A0A1Y7VIS8
swissprot - Q8R2F2
Ensembl - ENSMUSG00000021263
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 degs2ENSDARG00000042544Danio rerio
 DEGS2ENSGALG00000011213Gallus gallus
 DEGS2ENSG00000168350Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Degs1 / O09005 / Sphingolipid delta(4)-desaturase DES1 / O15121* / delta 4-desaturase, sphingolipid 1*ENSMUSG0000003863362
9130409I23Rik / RIKEN cDNA 9130409I23 gene / DEGS1* / O15121* / delta 4-desaturase, sphingolipid 1*ENSMUSG0000003876856


Protein motifs (from Interpro)
Interpro ID Name
 IPR005804  Fatty acid desaturase domain
 IPR011388  Sphingolipid delta4-desaturase
 IPR013866  Sphingolipid delta4-desaturase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006667 sphinganine metabolic process IGI
 biological_processGO:0030148 sphingolipid biosynthetic process IGI
 biological_processGO:0046513 ceramide biosynthetic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000170 sphingosine hydroxylase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042284 sphingolipid delta-4 desaturase activity IGI


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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