ENSG00000169035


Homo sapiens

Features
Gene ID: ENSG00000169035
  
Biological name :KLK7
  
Synonyms : kallikrein related peptidase 7 / KLK7 / P49862
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 50976482
Gene end: 50984099
  
Corresponding Affymetrix probe sets: 205778_at (Human Genome U133 Plus 2.0 Array)   239381_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304791
Ensembl peptide - ENSP00000469950
Ensembl peptide - ENSP00000470084
Ensembl peptide - ENSP00000470538
Ensembl peptide - ENSP00000375683
NCBI entrez gene - 5650     See in Manteia.
OMIM - 604438
RefSeq - NM_001207053
RefSeq - NM_001243126
RefSeq - NM_005046
RefSeq - NM_139277
RefSeq Peptide - NP_644806
RefSeq Peptide - NP_001193982
RefSeq Peptide - NP_001230055
RefSeq Peptide - NP_005037
swissprot - P49862
swissprot - Q6DTY1
swissprot - M0QYU8
swissprot - A0A024R4H6
Ensembl - ENSG00000169035
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034771Gallus gallus
 Klk7ENSMUSG00000030713Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLK5 / Q9Y337 / kallikrein related peptidase 5ENSG0000016775443
KLK12 / Q9UKR0 / kallikrein related peptidase 12ENSG0000018647442
KLK4 / Q9Y5K2 / kallikrein related peptidase 4ENSG0000016774941
KLK10 / O43240 / kallikrein related peptidase 10ENSG0000012945141


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002803 positive regulation of antibacterial peptide production IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0022617 extracellular matrix disassembly TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IMP
 cellular_componentGO:0097209 epidermal lamellar body IDA
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IMP
 molecular_functionGO:0008236 serine-type peptidase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000039068 CDH1 / P12830 / cadherin 1  / reaction






 

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