ENSG00000170011


Homo sapiens

Features
Gene ID: ENSG00000170011
  
Biological name :MYRIP
  
Synonyms : myosin VIIA and Rab interacting protein / MYRIP / Q8NFW9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.1
Gene start: 39808914
Gene end: 40260321
  
Corresponding Affymetrix probe sets: 214156_at (Human Genome U133 Plus 2.0 Array)   242730_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000438297
Ensembl peptide - ENSP00000400916
Ensembl peptide - ENSP00000413392
Ensembl peptide - ENSP00000301972
Ensembl peptide - ENSP00000379519
Ensembl peptide - ENSP00000389323
Ensembl peptide - ENSP00000398665
NCBI entrez gene - 25924     See in Manteia.
OMIM - 611790
RefSeq - XM_011533575
RefSeq - NM_001284423
RefSeq - NM_001284424
RefSeq - NM_001284425
RefSeq - NM_001284426
RefSeq - NM_015460
RefSeq Peptide - NP_001271352
RefSeq Peptide - NP_001271353
RefSeq Peptide - NP_001271354
RefSeq Peptide - NP_001271355
RefSeq Peptide - NP_056275
swissprot - Q8NFW9
swissprot - F8WFC5
Ensembl - ENSG00000170011
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myripENSDARG00000038814Danio rerio
 si:ch211-106h4.9ENSDARG00000075706Danio rerio
 ENSGALG00000041372Gallus gallus
 ENSGALG00000030855Gallus gallus
 MyripENSMUSG00000041794Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MLPH / Q9BV36 / melanophilinENSG0000011564818
MOBP / Q13875 / myelin-associated oligodendrocyte basic proteinENSG000001683146


Protein motifs (from Interpro)
Interpro ID Name
 IPR006788  Rab effector MyRIP/Melanophilin
 IPR010911  Rab-binding domain
 IPR011011  Zinc finger, FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0030050 vesicle transport along actin filament IBA
 biological_processGO:0032024 positive regulation of insulin secretion ISS
 cellular_componentGO:0000145 exocyst IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IBA
 cellular_componentGO:0031045 dense core granule ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0003779 actin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0017022 myosin binding IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051018 protein kinase A binding IEA


Pathways (from Reactome)
Pathway description
Insulin processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069974 P51159 / RAB27A / RAB27A, member RAS oncogene family  / complex
 ENSG00000197535 MYO5A / Q9Y4I1 / myosin VA  / complex






 

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