ENSG00000170324


Homo sapiens

Features
Gene ID: ENSG00000170324
  
Biological name :FRMPD2
  
Synonyms : FERM and PDZ domain containing 2 / FRMPD2 / Q68DX3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q11.22
Gene start: 48153088
Gene end: 48274870
  
Corresponding Affymetrix probe sets: 239275_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307079
Ensembl peptide - ENSP00000490362
Ensembl peptide - ENSP00000490201
Ensembl peptide - ENSP00000363317
NCBI entrez gene - 143162     See in Manteia.
OMIM - 613323
RefSeq - NM_001018071
RefSeq - NM_001318191
RefSeq Peptide - NP_001018081
RefSeq Peptide - NP_001305120
swissprot - Q68DX3
swissprot - A0A1B0GUQ4
swissprot - A0A1B0GV40
Ensembl - ENSG00000170324
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frmpd2ENSDARG00000074119Danio rerio
 FRMPD2ENSGALG00000006095Gallus gallus
 Frmpd2ENSMUSG00000108841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPN13 / Q12923 / protein tyrosine phosphatase, non-receptor type 13ENSG0000016362936
PTPN14 / Q15678 / protein tyrosine phosphatase, non-receptor type 14ENSG0000015210412
PTPN21 / Q16825 / protein tyrosine phosphatase, non-receptor type 21ENSG0000007077812
FRMD6 / Q96NE9 / FERM domain containing 6ENSG000001399268
FRMD1 / Q8N878 / FERM domain containing 1ENSG000001533037


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR001478  PDZ domain
 IPR011019  KIND domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR029906  FERM and PDZ domain-containing protein 2
 IPR035963  FERM superfamily, second domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0070830 bicellular tight junction assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005545 1-phosphatidylinositol binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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