ENSG00000139926


Homo sapiens

Features
Gene ID: ENSG00000139926
  
Biological name :FRMD6
  
Synonyms : FERM domain containing 6 / FRMD6 / Q96NE9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.1
Gene start: 51489100
Gene end: 51730727
  
Corresponding Affymetrix probe sets: 225464_at (Human Genome U133 Plus 2.0 Array)   225481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452529
Ensembl peptide - ENSP00000451977
Ensembl peptide - ENSP00000452122
Ensembl peptide - ENSP00000343899
Ensembl peptide - ENSP00000348550
Ensembl peptide - ENSP00000379068
Ensembl peptide - ENSP00000450667
Ensembl peptide - ENSP00000450735
Ensembl peptide - ENSP00000451157
Ensembl peptide - ENSP00000451453
NCBI entrez gene - 122786     See in Manteia.
OMIM - 614555
RefSeq - XM_017020968
RefSeq - NM_001042481
RefSeq - NM_001267046
RefSeq - NM_001267047
RefSeq - NM_152330
RefSeq - XM_006720029
RefSeq - XM_006720030
RefSeq - XM_011536423
RefSeq - XM_011536424
RefSeq - XM_017020967
RefSeq Peptide - NP_001253976
RefSeq Peptide - NP_689543
RefSeq Peptide - NP_001253975
RefSeq Peptide - NP_001035946
swissprot - H0YJ19
swissprot - H0YJC1
swissprot - Q96NE9
swissprot - G3V2L4
swissprot - G3V3V8
swissprot - G3V4T7
swissprot - G3V517
Ensembl - ENSG00000139926
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 frmd6ENSDARG00000002332Danio rerio
 FRMD6ENSGALG00000012374Gallus gallus
 Frmd6ENSMUSG00000048285Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FRMD1 / Q8N878 / FERM domain containing 1ENSG0000015330335
PTPN13 / Q12923 / protein tyrosine phosphatase, non-receptor type 13ENSG0000016362924
FRMPD2 / Q68DX3 / FERM and PDZ domain containing 2ENSG0000017032417
PTPN21 / Q16825 / protein tyrosine phosphatase, non-receptor type 21ENSG0000007077817
PTPN14 / Q15678 / protein tyrosine phosphatase, non-receptor type 14ENSG0000015210416


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003383 apical constriction IEA
 biological_processGO:0031032 actomyosin structure organization IBA
 biological_processGO:0032970 regulation of actin filament-based process IEA
 biological_processGO:0034613 cellular protein localization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043296 apical junction complex IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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