ENSG00000170860


Homo sapiens

Features
Gene ID: ENSG00000170860
  
Biological name :LSM3
  
Synonyms : LSM3 / LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated / P62310
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 14178358
Gene end: 14201119
  
Corresponding Affymetrix probe sets: 202209_at (Human Genome U133 Plus 2.0 Array)   236363_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302160
NCBI entrez gene - 27258     See in Manteia.
OMIM - 607283
RefSeq - NM_014463
RefSeq Peptide - NP_055278
swissprot - P62310
Ensembl - ENSG00000170860
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsm3ENSDARG00000089663Danio rerio
 LSM3ENSGALG00000031139Gallus gallus
 Lsm3ENSMUSG00000034192Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR010920  LSM domain superfamily
 IPR034105  Sm-like protein Lsm3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005688 U6 snRNP IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IBA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 cellular_componentGO:1990726 Lsm1-7-Pat1 complex IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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