ENSG00000170899


Homo sapiens

Features
Gene ID: ENSG00000170899
  
Biological name :GSTA4
  
Synonyms : glutathione S-transferase alpha 4 / GSTA4 / O15217
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.2
Gene start: 52977948
Gene end: 52995378
  
Corresponding Affymetrix probe sets: 202967_at (Human Genome U133 Plus 2.0 Array)   235405_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394228
Ensembl peptide - ENSP00000359998
Ensembl peptide - ENSP00000359999
Ensembl peptide - ENSP00000360002
NCBI entrez gene - 2941     See in Manteia.
OMIM - 605450
RefSeq - XM_011514535
RefSeq - NM_001512
RefSeq - XM_005249035
RefSeq - XM_011514534
RefSeq Peptide - NP_001503
swissprot - Q5JW88
swissprot - A0A024RD58
swissprot - O15217
Ensembl - ENSG00000170899
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsta.1ENSDARG00000113274Danio rerio
 gsta.1ENSDARG00000090228Danio rerio
 gsta.2ENSDARG00000039832Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTA2 / P09210 / glutathione S-transferase alpha 2ENSG0000024406754
GSTA1 / P08263 / glutathione S-transferase alpha 1ENSG0000024395554
GSTA3 / Q16772 / glutathione S-transferase alpha 3ENSG0000017415653
GSTA5 / Q7RTV2 / glutathione S-transferase alpha 5ENSG0000018279353
HPGDS / O60760 / hematopoietic prostaglandin D synthaseENSG0000016310621


Protein motifs (from Interpro)
Interpro ID Name
 IPR003080  Glutathione S-transferase, alpha class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IDA
 biological_processGO:0006805 xenobiotic metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Glutathione conjugation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000170899 GSTA4 / O15217 / glutathione S-transferase alpha 4  / complex






 

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