ENSG00000244067


Homo sapiens

Features
Gene ID: ENSG00000244067
  
Biological name :GSTA2
  
Synonyms : glutathione S-transferase alpha 2 / GSTA2 / P09210
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.2
Gene start: 52750089
Gene end: 52763569
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000420168
NCBI entrez gene - 2939     See in Manteia.
OMIM - 138360
RefSeq - XM_011514532
RefSeq - NM_000846
RefSeq Peptide - NP_000837
swissprot - P09210
swissprot - A0A140VKE2
Ensembl - ENSG00000244067
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsta.1ENSDARG00000090228Danio rerio
 gsta.1ENSDARG00000113274Danio rerio
 gsta.2ENSDARG00000039832Danio rerio
 ENSGALG00000028551Gallus gallus
 ENSGALG00000038652Gallus gallus
 GSTA3ENSGALG00000016325Gallus gallus
 Gm10639ENSMUSG00000074179Mus musculus
 Gm3776ENSMUSG00000111709Mus musculus
 Gsta1ENSMUSG00000074183Mus musculus
 Gsta2ENSMUSG00000057933Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTA1 / P08263 / glutathione S-transferase alpha 1ENSG0000024395595
GSTA5 / Q7RTV2 / glutathione S-transferase alpha 5ENSG0000018279389
GSTA3 / Q16772 / glutathione S-transferase alpha 3ENSG0000017415689
GSTA4 / O15217 / glutathione S-transferase alpha 4ENSG0000017089954
HPGDS / O60760 / hematopoietic prostaglandin D synthaseENSG0000016310621


Protein motifs (from Interpro)
Interpro ID Name
 IPR003080  Glutathione S-transferase, alpha class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process ISS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEP
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome TAS
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000243955 GSTA1 / P08263 / glutathione S-transferase alpha 1  / complex
 ENSG00000244067 GSTA2 / P09210 / glutathione S-transferase alpha 2  / complex






 

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