ENSG00000163106


Homo sapiens

Features
Gene ID: ENSG00000163106
  
Biological name :HPGDS
  
Synonyms : hematopoietic prostaglandin D synthase / HPGDS / O60760
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q22.3
Gene start: 94298535
Gene end: 94342876
  
Corresponding Affymetrix probe sets: 206726_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295256
NCBI entrez gene - 27306     See in Manteia.
OMIM - 602598
RefSeq - NM_014485
RefSeq - XM_005262932
RefSeq Peptide - NP_055300
swissprot - O60760
Ensembl - ENSG00000163106
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HPGDSENSGALG00000010402Gallus gallus
 HpgdsENSMUSG00000029919Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTA3 / Q16772 / glutathione S-transferase alpha 3ENSG0000017415625
GSTA1 / P08263 / glutathione S-transferase alpha 1ENSG0000024395524
GSTA2 / P09210 / glutathione S-transferase alpha 2ENSG0000024406724
GSTA4 / O15217 / glutathione S-transferase alpha 4ENSG0000017089923
GSTA5 / Q7RTV2 / glutathione S-transferase alpha 5ENSG0000018279323


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001516 prostaglandin biosynthetic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006693 prostaglandin metabolic process IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007626 locomotory behavior TAS
 biological_processGO:0019371 cyclooxygenase pathway TAS
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 biological_processGO:2000255 negative regulation of male germ cell proliferation IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004364 glutathione transferase activity TAS
 molecular_functionGO:0004667 prostaglandin-D synthase activity TAS
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163106 HPGDS / O60760 / hematopoietic prostaglandin D synthase  / complex






 

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