ENSG00000171206


Homo sapiens

Features
Gene ID: ENSG00000171206
  
Biological name :TRIM8
  
Synonyms : Q9BZR9 / TRIM8 / tripartite motif containing 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.32
Gene start: 102642310
Gene end: 102660680
  
Corresponding Affymetrix probe sets: 221012_s_at (Human Genome U133 Plus 2.0 Array)   223131_s_at (Human Genome U133 Plus 2.0 Array)   223132_s_at (Human Genome U133 Plus 2.0 Array)   228015_s_at (Human Genome U133 Plus 2.0 Array)   231161_x_at (Human Genome U133 Plus 2.0 Array)   238044_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000496301
Ensembl peptide - ENSP00000496615
Ensembl peptide - ENSP00000302120
Ensembl peptide - ENSP00000473428
Ensembl peptide - ENSP00000493545
Ensembl peptide - ENSP00000494130
Ensembl peptide - ENSP00000494181
Ensembl peptide - ENSP00000494335
Ensembl peptide - ENSP00000494508
NCBI entrez gene - 81603     See in Manteia.
OMIM - 606125
RefSeq - NM_030912
RefSeq Peptide - NP_112174
swissprot - Q9BZR9
swissprot - R4GN03
Ensembl - ENSG00000171206
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim8aENSDARG00000090512Danio rerio
 trim8bENSDARG00000060729Danio rerio
 TRIM8ENSGALG00000036785Gallus gallus
 Trim8ENSMUSG00000025034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0032897 negative regulation of viral transcription IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0046597 negative regulation of viral entry into host cell IDA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:1900182 positive regulation of protein localization to nucleus IMP
 biological_processGO:1902187 negative regulation of viral release from host cell IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016605 PML body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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