ENSMUSG00000025034


Mus musculus

Features
Gene ID: ENSMUSG00000025034
  
Biological name :Trim8
  
Synonyms : Probable E3 ubiquitin-protein ligase TRIM8 / Q99PJ2 / Trim8
  
Possible biological names infered from orthology : Q9BZR9 / tripartite motif containing 8
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 46501648
Gene end: 46516444
  
Corresponding Affymetrix probe sets: 10463661 (MoGene1.0st)   1418577_at (Mouse Genome 430 2.0 Array)   1438679_at (Mouse Genome 430 2.0 Array)   1460237_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026008
NCBI entrez gene - 93679     See in Manteia.
MGI - MGI:1933302
RefSeq - NM_053100
RefSeq - XM_006527488
RefSeq Peptide - NP_444330
swissprot - Q99PJ2
Ensembl - ENSMUSG00000025034
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim8aENSDARG00000090512Danio rerio
 trim8bENSDARG00000060729Danio rerio
 TRIM8ENSGALG00000036785Gallus gallus
 TRIM8ENSG00000171206Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0010508 positive regulation of autophagy ISS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0032897 negative regulation of viral transcription IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0045087 innate immune response ISO
 biological_processGO:0046597 negative regulation of viral entry into host cell IDA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:1900182 positive regulation of protein localization to nucleus IMP
 biological_processGO:1902187 negative regulation of viral release from host cell IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016605 PML body ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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