ENSG00000171566


Homo sapiens

Features
Gene ID: ENSG00000171566
  
Biological name :PLRG1
  
Synonyms : O43660 / pleiotropic regulator 1 / PLRG1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q31.3
Gene start: 154535006
Gene end: 154550435
  
Corresponding Affymetrix probe sets: 225194_at (Human Genome U133 Plus 2.0 Array)   227246_at (Human Genome U133 Plus 2.0 Array)   238137_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424417
Ensembl peptide - ENSP00000426497
Ensembl peptide - ENSP00000425914
Ensembl peptide - ENSP00000425147
Ensembl peptide - ENSP00000424616
Ensembl peptide - ENSP00000303191
Ensembl peptide - ENSP00000423454
NCBI entrez gene - 5356     See in Manteia.
OMIM - 605961
RefSeq - NM_001201564
RefSeq - NM_002669
RefSeq Peptide - NP_001188493
RefSeq Peptide - NP_002660
swissprot - D6RE04
swissprot - O43660
swissprot - D6RA26
swissprot - B7Z982
swissprot - H0YA24
swissprot - H0YAA2
Ensembl - ENSG00000171566
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plrg1ENSDARG00000037283Danio rerio
 PLRG1ENSGALG00000009257Gallus gallus
 Plrg1ENSMUSG00000027998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STRN3 / Q13033 / striatin 3ENSG0000019679221
STRN4 / Q9NRL3 / striatin 4ENSG0000009037220
STRN / O43815 / striatinENSG0000011580820


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005662 DNA replication factor A complex IDA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IDA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IBA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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