ENSDARG00000037283


Danio rerio

Features
Gene ID: ENSDARG00000037283
  
Biological name :plrg1
  
Synonyms : pleiotropic regulator 1 / plrg1
  
Possible biological names infered from orthology : O43660 / Q922V4
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 25650917
Gene end: 25666604
  
Corresponding Affymetrix probe sets: Dr.11443.1.S1_at (Zebrafish Array)   NM_213440_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054234
NCBI entrez gene - 100004402     See in Manteia.
RefSeq - NM_213440
RefSeq Peptide - NP_998605
swissprot - Q5U3B5
ZFIN ID - ZDB-GENE-040426-2787
Ensembl - ENSDARG00000037283
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLRG1ENSGALG00000009257Gallus gallus
 PLRG1ENSG00000171566Homo sapiens
 Plrg1ENSMUSG00000027998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
strn4 / striatin, calmodulin binding protein 4 / Q9NRL3* / striatin 4*ENSDARG0000010290219
strn / striatin, calmodulin binding protein / O43815* / striatin*ENSDARG0000010001118
strn3 / striatin, calmodulin binding protein 3 / Q13033* / Q9ERG2* / striatin 3*ENSDARG0000000172918


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator IMP
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0005662 DNA replication factor A complex IBA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IBA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000084 yolk yolk quality , abnormal
yolk circular , abnormal
yolk grey , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000396 nervous system nervous system quality , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism apoptotic , abnormal
whole organism necrotic , abnormal
whole organism viability , abnormal
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 ZFA:0001114 head head flat , abnormal
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 ZFA:0001115 trunk trunk decreased length , abnormal
trunk decreased thickness , abnormal
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 ZFA:0001117 post-vent region post-vent region truncated , abnormal
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 ZFA:0009248 neuron neuron increased sensitivity to irradiation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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