ENSG00000171858


Homo sapiens

Features
Gene ID: ENSG00000171858
  
Biological name :RPS21
  
Synonyms : P63220 / ribosomal protein S21 / RPS21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.33
Gene start: 62387116
Gene end: 62388520
  
Corresponding Affymetrix probe sets: 200834_s_at (Human Genome U133 Plus 2.0 Array)   214097_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000345957
Ensembl peptide - ENSP00000359593
Ensembl peptide - ENSP00000359624
Ensembl peptide - ENSP00000388332
NCBI entrez gene - 6227     See in Manteia.
OMIM - 180477
RefSeq - NM_001024
RefSeq Peptide - NP_001015
swissprot - P63220
swissprot - Q6FGH5
swissprot - Q8WVC2
swissprot - Q9BYK1
swissprot - Q9BYK2
Ensembl - ENSG00000171858
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps21ENSDARG00000025850Danio rerio
 RPS21ENSGALG00000005338Gallus gallus
 Rps21ENSMUSG00000039001Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001931  Ribosomal protein S21e
 IPR018279  Ribosomal protein S21e, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0000461 endonucleolytic cleavage to generate mature 3"-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0002181 cytoplasmic translation IDA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0015935 small ribosomal subunit HDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit NAS
 cellular_componentGO:0042788 polysomal ribosome IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0047485 protein N-terminus binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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