ENSG00000172725


Homo sapiens

Features
Gene ID: ENSG00000172725
  
Biological name :CORO1B
  
Synonyms : CORO1B / coronin 1B / Q9BR76
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.2
Gene start: 67435510
Gene end: 67443821
  
Corresponding Affymetrix probe sets: 204960_at (Human Genome U133 Plus 2.0 Array)   221754_s_at (Human Genome U133 Plus 2.0 Array)   64486_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000438056
Ensembl peptide - ENSP00000486585
Ensembl peptide - ENSP00000479949
Ensembl peptide - ENSP00000445330
Ensembl peptide - ENSP00000340211
Ensembl peptide - ENSP00000377471
NCBI entrez gene - 57175     See in Manteia.
OMIM - 609849
RefSeq - NM_001018070
RefSeq - NM_020441
RefSeq Peptide - NP_001018080
RefSeq Peptide - NP_065174
swissprot - Q9BR76
swissprot - A0A024R5K1
swissprot - F5H0D2
swissprot - F5H390
swissprot - A0A087WW53
Ensembl - ENSG00000172725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 coro1bENSDARG00000008660Danio rerio
 Coro1bENSMUSG00000024835Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CORO1C / Q9ULV4 / coronin 1CENSG0000011088071
CORO6 / Q6QEF8 / coronin 6ENSG0000016754966
CORO1A / P31146 / coronin 1AENSG0000010287964
CORO2A / Q92828 / coronin 2AENSG0000010678944
CORO2B / Q9UQ03 / coronin 2BENSG0000010364742
CORO7-PAM16 / CORO7-PAM16 readthroughENSG0000010342631
CORO7 / P57737 / coronin 7ENSG0000026224631
PAM16 / Q9Y3D7 / presequence translocase associated motor 16ENSG000002179300


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015048  Domain of unknown function DUF1899
 IPR015505  Coronin
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR027340  Coronin 1B
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016477 cell migration IDA
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:0031529 ruffle organization IDA
 biological_processGO:0034315 regulation of Arp2/3 complex-mediated actin nucleation IC
 biological_processGO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IDA
 biological_processGO:0035767 endothelial cell chemotaxis IMP
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IMP
 biological_processGO:0042060 wound healing IDA
 biological_processGO:0051017 actin filament bundle assembly IDA
 biological_processGO:0071672 negative regulation of smooth muscle cell chemotaxis IMP
 biological_processGO:0090135 actin filament branching IDA
 biological_processGO:1902463 protein localization to cell leading edge IDA
 biological_processGO:2000394 positive regulation of lamellipodium morphogenesis IDA
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0031252 cell leading edge IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051015 actin filament binding IMP
 molecular_functionGO:0071933 Arp2/3 complex binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr