ENSG00000110880


Homo sapiens

Features
Gene ID: ENSG00000110880
  
Biological name :CORO1C
  
Synonyms : CORO1C / coronin 1C / Q9ULV4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 108645109
Gene end: 108731596
  
Corresponding Affymetrix probe sets: 221676_s_at (Human Genome U133 Plus 2.0 Array)   222409_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448527
Ensembl peptide - ENSP00000448195
Ensembl peptide - ENSP00000449330
Ensembl peptide - ENSP00000449658
Ensembl peptide - ENSP00000261401
Ensembl peptide - ENSP00000394496
Ensembl peptide - ENSP00000415554
Ensembl peptide - ENSP00000438341
Ensembl peptide - ENSP00000447049
Ensembl peptide - ENSP00000447337
Ensembl peptide - ENSP00000447534
Ensembl peptide - ENSP00000447989
Ensembl peptide - ENSP00000448130
NCBI entrez gene - 23603     See in Manteia.
OMIM - 605269
RefSeq - XM_017019123
RefSeq - NM_001105237
RefSeq - NM_001276471
RefSeq - NM_014325
RefSeq - XM_017019121
RefSeq - XM_017019122
RefSeq Peptide - NP_001263400
RefSeq Peptide - NP_055140
RefSeq Peptide - NP_001098707
swissprot - H0YHL7
swissprot - Q9ULV4
swissprot - A0A024RBI5
swissprot - B4E3S0
swissprot - F8VRE9
swissprot - F8VSA4
swissprot - F8VTT6
swissprot - F8VV53
swissprot - F8VUX3
swissprot - F8VVB7
swissprot - F8W1H8
Ensembl - ENSG00000110880
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 coro1caENSDARG00000035598Danio rerio
 coro1cbENSDARG00000021193Danio rerio
 CORO1CENSGALG00000004901Gallus gallus
 Coro1cENSMUSG00000004530Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CORO1B / Q9BR76 / coronin 1BENSG0000017272566
CORO6 / Q6QEF8 / coronin 6ENSG0000016754961
CORO1A / P31146 / coronin 1AENSG0000010287956
CORO2A / Q92828 / coronin 2AENSG0000010678939
CORO2B / Q9UQ03 / coronin 2BENSG0000010364739
CORO7 / P57737 / coronin 7ENSG0000026224629
CORO7-PAM16 / CORO7-PAM16 readthroughENSG0000010342629
PAM16 / Q9Y3D7 / presequence translocase associated motor 16ENSG000002179300


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015048  Domain of unknown function DUF1899
 IPR015505  Coronin
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR027333  Coronin 1C
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0001932 regulation of protein phosphorylation IGI
 biological_processGO:0001933 negative regulation of protein phosphorylation IMP
 biological_processGO:0006909 phagocytosis TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0010632 regulation of epithelial cell migration IGI
 biological_processGO:0010633 negative regulation of epithelial cell migration IMP
 biological_processGO:0010762 regulation of fibroblast migration IEA
 biological_processGO:0030036 actin cytoskeleton organization IBA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IMP
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0051893 regulation of focal adhesion assembly IGI
 biological_processGO:0051895 negative regulation of focal adhesion assembly IMP
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:1900024 regulation of substrate adhesion-dependent cell spreading IGI
 biological_processGO:1900025 negative regulation of substrate adhesion-dependent cell spreading IMP
 biological_processGO:1900027 regulation of ruffle assembly IEA
 biological_processGO:2000394 positive regulation of lamellipodium morphogenesis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IDA
 cellular_componentGO:0016600 flotillin complex IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0048365 Rac GTPase binding IEA
 molecular_functionGO:0051015 actin filament binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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