ENSG00000173638


Homo sapiens

Features
Gene ID: ENSG00000173638
  
Biological name :SLC19A1
  
Synonyms : P41440 / SLC19A1 / solute carrier family 19 member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q22.3
Gene start: 45493572
Gene end: 45544411
  
Corresponding Affymetrix probe sets: 1555952_at (Human Genome U133 Plus 2.0 Array)   1555953_at (Human Genome U133 Plus 2.0 Array)   209775_x_at (Human Genome U133 Plus 2.0 Array)   209776_s_at (Human Genome U133 Plus 2.0 Array)   209777_s_at (Human Genome U133 Plus 2.0 Array)   211576_s_at (Human Genome U133 Plus 2.0 Array)   229639_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411345
Ensembl peptide - ENSP00000401850
Ensembl peptide - ENSP00000435780
Ensembl peptide - ENSP00000457278
Ensembl peptide - ENSP00000441772
Ensembl peptide - ENSP00000308895
Ensembl peptide - ENSP00000369347
Ensembl peptide - ENSP00000393988
NCBI entrez gene - 6573     See in Manteia.
OMIM - 600424
RefSeq - XM_017028446
RefSeq - XM_011529698
RefSeq - XM_011529700
RefSeq - XM_011529701
RefSeq - XM_011529702
RefSeq - XM_011529703
RefSeq - XM_011529704
RefSeq - XM_011529706
RefSeq - XM_011529709
RefSeq - XM_017028443
RefSeq - XM_017028444
RefSeq - XM_017028445
RefSeq - NM_001205206
RefSeq - NM_001205207
RefSeq - NM_194255
RefSeq - XM_005261164
RefSeq - XM_011529696
RefSeq Peptide - NP_919231
RefSeq Peptide - NP_001192135
RefSeq Peptide - NP_001192136
RefSeq Peptide - NP_001339440
RefSeq Peptide - NP_001339441
swissprot - C9J8K6
swissprot - P41440
swissprot - C9JKP4
swissprot - H0Y4T2
swissprot - H3BTQ3
swissprot - E9PIL5
Ensembl - ENSG00000173638
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc19a1ENSDARG00000033993Danio rerio
 SLC19A1ENSGALG00000030511Gallus gallus
 P41438ENSMUSG00000001436Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BZV2 / SLC19A3 / solute carrier family 19 member 3ENSG0000013591732
O60779 / SLC19A2 / solute carrier family 19 member 2ENSG0000011747931


Protein motifs (from Interpro)
Interpro ID Name
 IPR002666  Reduced folate carrier
 IPR020846  Major facilitator superfamily domain
 IPR028339  Folate transporter 1
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015884 folic acid transport IEA
 biological_processGO:0035461 vitamin transmembrane transport IEA
 biological_processGO:0046655 folic acid metabolic process TAS
 biological_processGO:0051180 vitamin transport IEA
 biological_processGO:0051958 methotrexate transport IEA
 biological_processGO:0098838 folate transmembrane transport IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IDA
 molecular_functionGO:0005542 folic acid binding IBA
 molecular_functionGO:0008517 folic acid transmembrane transporter activity IEA
 molecular_functionGO:0008518 folate:anion antiporter activity IDA
 molecular_functionGO:0015350 methotrexate transmembrane transporter activity IEA
 molecular_functionGO:0090482 vitamin transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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