ENSG00000173744


Homo sapiens

Features
Gene ID: ENSG00000173744
  
Biological name :AGFG1
  
Synonyms : AGFG1 / ArfGAP with FG repeats 1 / P52594
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q36.3
Gene start: 227472152
Gene end: 227561214
  
Corresponding Affymetrix probe sets: 213926_s_at (Human Genome U133 Plus 2.0 Array)   213928_s_at (Human Genome U133 Plus 2.0 Array)   218091_at (Human Genome U133 Plus 2.0 Array)   218092_s_at (Human Genome U133 Plus 2.0 Array)   226561_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387218
Ensembl peptide - ENSP00000387154
Ensembl peptide - ENSP00000387282
Ensembl peptide - ENSP00000405429
Ensembl peptide - ENSP00000396469
Ensembl peptide - ENSP00000312059
Ensembl peptide - ENSP00000362775
NCBI entrez gene - 3267     See in Manteia.
OMIM - 600862
RefSeq - XM_006712480
RefSeq - NM_001135187
RefSeq - NM_001135188
RefSeq - NM_001135189
RefSeq - NM_004504
RefSeq - XM_005246516
RefSeq - XM_006712478
RefSeq - XM_006712479
RefSeq Peptide - NP_001128661
RefSeq Peptide - NP_004495
RefSeq Peptide - NP_001128660
RefSeq Peptide - NP_001128659
swissprot - P52594
swissprot - A0A0S2Z444
swissprot - C9J2I0
swissprot - B8ZZY2
swissprot - H7C0S7
Ensembl - ENSG00000173744
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agfg1aENSDARG00000030020Danio rerio
 agfg1bENSDARG00000019526Danio rerio
 AGFG1ENSGALG00000003052Gallus gallus
 Agfg1ENSMUSG00000026159Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGFG2 / O95081 / ArfGAP with FG repeats 2ENSG0000010635136


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001675 acrosome assembly IEA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007289 spermatid nucleus differentiation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045109 intermediate filament organization IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124333 VAMP7 / P51809 / vesicle associated membrane protein 7  / reaction / complex






 

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