ENSG00000174579


Homo sapiens

Features
Gene ID: ENSG00000174579
  
Biological name :MSL2
  
Synonyms : MSL2 / MSL complex subunit 2 / Q9HCI7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.3
Gene start: 136148922
Gene end: 136197241
  
Corresponding Affymetrix probe sets: 218733_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311827
Ensembl peptide - ENSP00000418752
Ensembl peptide - ENSP00000418655
Ensembl peptide - ENSP00000417956
Ensembl peptide - ENSP00000387948
NCBI entrez gene - 55167     See in Manteia.
OMIM - 614802
RefSeq - XM_005247571
RefSeq - XM_011512949
RefSeq - XM_006713684
RefSeq - NM_001145417
RefSeq - NM_018133
RefSeq Peptide - NP_001138889
RefSeq Peptide - NP_060603
swissprot - Q9HCI7
swissprot - C9J5S2
swissprot - C9IZ03
swissprot - C9IZG7
Ensembl - ENSG00000174579
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msl2aENSDARG00000038909Danio rerio
 msl2bENSDARG00000039430Danio rerio
 MSL2ENSGALG00000039294Gallus gallus
 Msl2ENSMUSG00000066415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR032043  E3 ubiquitin-protein ligase Msl2, zinc RING finger
 IPR032049  E3 ubiquitin-protein ligase Msl2, CXC domain
 IPR033467  Tesmin/TSO1-like CXC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043984 histone H4-K16 acetylation IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0072487 MSL complex IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103510 KAT8 / Q9H7Z6 / lysine acetyltransferase 8  / complex
 ENSG00000005302 MSL3 / Q8N5Y2 / MSL complex subunit 3  / complex
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / reaction
 ENSG00000188895 MSL1 / Q68DK7 / male specific lethal 1 homolog  / complex






 

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