ENSG00000174744


Homo sapiens

Features
Gene ID: ENSG00000174744
  
Biological name :BRMS1
  
Synonyms : breast cancer metastasis suppressor 1 / BRMS1 / Q9HCU9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.2
Gene start: 66337333
Gene end: 66345125
  
Corresponding Affymetrix probe sets: 215631_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396052
Ensembl peptide - ENSP00000434591
Ensembl peptide - ENSP00000433740
Ensembl peptide - ENSP00000431510
Ensembl peptide - ENSP00000353042
NCBI entrez gene - 25855     See in Manteia.
OMIM - 606259
RefSeq - NM_001024957
RefSeq - NM_015399
RefSeq Peptide - NP_001020128
RefSeq Peptide - NP_056214
swissprot - Q9HCU9
swissprot - E9PJF5
swissprot - G5E9I4
swissprot - H0YCF7
swissprot - E9PPD1
Ensembl - ENSG00000174744
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brms1ENSDARG00000051955Danio rerio
 Brms1ENSMUSG00000080268Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRMS1L / Q5PSV4 / breast cancer metastasis-suppressor 1 likeENSG0000010091646


Protein motifs (from Interpro)
Interpro ID Name
 IPR013907  Sds3-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0016575 histone deacetylation IBA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0042981 regulation of apoptotic process IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0090312 positive regulation of protein deacetylation IDA
 biological_processGO:2000210 positive regulation of anoikis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0070822 Sin3-type complex IBA
 molecular_functionGO:0004407 histone deacetylase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IBA
 molecular_functionGO:0051059 NF-kappaB binding IDA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000032219 ARID4A / P29374 / AT-rich interaction domain 4A  / complex
 ENSG00000164576 Q9HAJ7 / SAP30L / SAP30 like  / complex






 

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