ENSG00000164576


Homo sapiens

Features
Gene ID: ENSG00000164576
  
Biological name :SAP30L
  
Synonyms : Q9HAJ7 / SAP30L / SAP30 like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q33.2
Gene start: 154445957
Gene end: 154461054
  
Corresponding Affymetrix probe sets: 219129_s_at (Human Genome U133 Plus 2.0 Array)   222831_at (Human Genome U133 Plus 2.0 Array)   225509_at (Human Genome U133 Plus 2.0 Array)   226772_s_at (Human Genome U133 Plus 2.0 Array)   232135_at (Human Genome U133 Plus 2.0 Array)   239802_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000297109
Ensembl peptide - ENSP00000390927
Ensembl peptide - ENSP00000416393
NCBI entrez gene - 79685     See in Manteia.
OMIM - 610398
RefSeq - NM_001131063
RefSeq - NM_001131062
RefSeq - NM_024632
RefSeq Peptide - NP_001124534
RefSeq Peptide - NP_001124535
RefSeq Peptide - NP_078908
swissprot - Q9HAJ7
Ensembl - ENSG00000164576
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NYV5ENSDARG00000030213Danio rerio
 SAP30LENSGALG00000028994Gallus gallus
 Q5SQF8ENSMUSG00000020519Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SAP30 / O75446 / Sin3A associated protein 30ENSG0000016410570


Protein motifs (from Interpro)
Interpro ID Name
 IPR024145  Histone deacetylase complex subunit SAP30/SAP30-like
 IPR025717  Histone deacetylase complex subunit SAP30 zinc-finger
 IPR025718  Histone deacetylase complex subunit SAP30, Sin3 binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0016575 histone deacetylation IEA
 cellular_componentGO:0000118 histone deacetylase complex IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IBA
 molecular_functionGO:0004407 histone deacetylase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0010314 phosphatidylinositol-5-phosphate binding IDA
 molecular_functionGO:0031491 nucleosome binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0044378 non-sequence-specific DNA binding, bending IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
NoRC negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000032219 ARID4A / P29374 / AT-rich interaction domain 4A  / complex
 ENSG00000174744 BRMS1 / Q9HCU9 / breast cancer metastasis suppressor 1  / complex






 

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