ENSG00000032219


Homo sapiens

Features
Gene ID: ENSG00000032219
  
Biological name :ARID4A
  
Synonyms : ARID4A / AT-rich interaction domain 4A / P29374
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q23.1
Gene start: 58298385
Gene end: 58373887
  
Corresponding Affymetrix probe sets: 205062_x_at (Human Genome U133 Plus 2.0 Array)   230141_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378597
Ensembl peptide - ENSP00000347602
Ensembl peptide - ENSP00000392567
Ensembl peptide - ENSP00000416053
Ensembl peptide - ENSP00000415872
Ensembl peptide - ENSP00000410417
Ensembl peptide - ENSP00000397368
Ensembl peptide - ENSP00000344556
NCBI entrez gene - 5926     See in Manteia.
OMIM - 180201
RefSeq - XM_017021565
RefSeq - NM_002892
RefSeq - NM_023000
RefSeq - NM_023001
RefSeq - XM_005267964
RefSeq - XM_005267965
RefSeq - XM_017021560
RefSeq - XM_017021561
RefSeq - XM_017021562
RefSeq - XM_017021563
RefSeq - XM_017021564
RefSeq Peptide - NP_075376
RefSeq Peptide - NP_075377
RefSeq Peptide - NP_002883
swissprot - A0A024R6A2
swissprot - A0A024R680
swissprot - F8WAR5
swissprot - H7C485
swissprot - A0A024R657
swissprot - P29374
swissprot - C9JIF4
swissprot - C9J1W3
Ensembl - ENSG00000032219
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arid4aENSDARG00000043873Danio rerio
 ARID4AENSGALG00000012037Gallus gallus
 Arid4aENSMUSG00000048118Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARID4B / Q4LE39 / AT-rich interaction domain 4BENSG0000005426746
ARID5B / Q14865 / AT-rich interaction domain 5BENSG0000015034712
ARID5A / Q03989 / AT-rich interaction domain 5AENSG000001968437


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001606  ARID DNA-binding domain
 IPR002999  Tudor domain
 IPR012603  RBB1NT
 IPR016197  Chromo-like domain superfamily
 IPR025995  RNA binding activity-knot of a chromodomain
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0034773 histone H4-K20 trimethylation IEA
 biological_processGO:0036124 histone H3-K9 trimethylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048821 erythrocyte development IEA
 biological_processGO:0080182 histone H3-K4 trimethylation IEA
 biological_processGO:0097368 establishment of Sertoli cell barrier IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0004407 histone deacetylase activity TAS
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000174744 BRMS1 / Q9HCU9 / breast cancer metastasis suppressor 1  / complex
 ENSG00000164576 Q9HAJ7 / SAP30L / SAP30 like  / complex






 

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