ENSG00000150347


Homo sapiens

Features
Gene ID: ENSG00000150347
  
Biological name :ARID5B
  
Synonyms : ARID5B / AT-rich interaction domain 5B / Q14865
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q21.2
Gene start: 61901300
Gene end: 62096944
  
Corresponding Affymetrix probe sets: 1558000_at (Human Genome U133 Plus 2.0 Array)   1558001_s_at (Human Genome U133 Plus 2.0 Array)   212614_at (Human Genome U133 Plus 2.0 Array)   235404_at (Human Genome U133 Plus 2.0 Array)   241969_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000279873
Ensembl peptide - ENSP00000308862
Ensembl peptide - ENSP00000494412
NCBI entrez gene - 84159     See in Manteia.
OMIM - 608538
RefSeq - XM_017016765
RefSeq - NM_001244638
RefSeq - NM_032199
RefSeq - XM_011540262
RefSeq Peptide - NP_001231567
RefSeq Peptide - NP_115575
swissprot - Q14865
Ensembl - ENSG00000150347
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arid5bENSDARG00000037196Danio rerio
 ARID5BENSGALG00000031534Gallus gallus
 Arid5bENSMUSG00000019947Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARID5A / Q03989 / AT-rich interaction domain 5AENSG0000019684318
ARID4A / P29374 / AT-rich interaction domain 4AENSG0000003221913
ARID4B / Q4LE39 / AT-rich interaction domain 4BENSG0000005426713


Protein motifs (from Interpro)
Interpro ID Name
 IPR001606  ARID DNA-binding domain
 IPR030408  AT-rich interactive domain-containing protein 5B
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001889 liver development TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006807 nitrogen compound metabolic process IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010761 fibroblast migration IEA
 biological_processGO:0016577 histone demethylation IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated TAS
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0048468 cell development IEA
 biological_processGO:0048644 muscle organ morphogenesis IEA
 biological_processGO:0048705 skeletal system morphogenesis IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IDA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060325 face morphogenesis IEA
 biological_processGO:0060612 adipose tissue development ISS
 biological_processGO:0060613 fat pad development IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032452 histone demethylase activity TAS
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197724 PHF2 / O75151 / PHD finger protein 2  / complex






 

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