ENSG00000054267


Homo sapiens

Features
Gene ID: ENSG00000054267
  
Biological name :ARID4B
  
Synonyms : ARID4B / AT-rich interaction domain 4B / Q4LE39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.3
Gene start: 235131634
Gene end: 235328219
  
Corresponding Affymetrix probe sets: 212591_at (Human Genome U133 Plus 2.0 Array)   214139_at (Human Genome U133 Plus 2.0 Array)   214943_s_at (Human Genome U133 Plus 2.0 Array)   221230_s_at (Human Genome U133 Plus 2.0 Array)   223111_x_at (Human Genome U133 Plus 2.0 Array)   224322_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416063
Ensembl peptide - ENSP00000394663
Ensembl peptide - ENSP00000420620
Ensembl peptide - ENSP00000264183
Ensembl peptide - ENSP00000264184
Ensembl peptide - ENSP00000355562
Ensembl peptide - ENSP00000391497
NCBI entrez gene - 51742     See in Manteia.
OMIM - 609696
RefSeq - XM_017001471
RefSeq - NM_001206794
RefSeq - NM_016374
RefSeq - NM_031371
RefSeq - XM_006711781
RefSeq - XM_011544212
RefSeq - XM_017001468
RefSeq - XM_017001469
RefSeq - XM_017001470
RefSeq Peptide - NP_001193723
RefSeq Peptide - NP_057458
RefSeq Peptide - NP_112739
swissprot - X6RCR8
swissprot - H0Y7Y8
swissprot - A0A024R3R1
swissprot - H7C5R6
swissprot - Q4LE39
Ensembl - ENSG00000054267
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tomm20aENSDARG00000090656Danio rerio
 ARID4BENSGALG00000034003Gallus gallus
 A2CG63ENSMUSG00000039219Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARID4A / P29374 / AT-rich interaction domain 4AENSG0000003221944
ARID5B / Q14865 / AT-rich interaction domain 5BENSG0000015034712
ARID5A / Q03989 / AT-rich interaction domain 5AENSG000001968439


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001606  ARID DNA-binding domain
 IPR002999  Tudor domain
 IPR012603  RBB1NT
 IPR016197  Chromo-like domain superfamily
 IPR025995  RNA binding activity-knot of a chromodomain
 IPR028853  AT-rich interactive domain-containing protein 4B
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0034773 histone H4-K20 trimethylation IEA
 biological_processGO:0036124 histone H3-K9 trimethylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0097368 establishment of Sertoli cell barrier IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004407 histone deacetylase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
NoRC negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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