ENSMUSG00000039219


Mus musculus

Features
Gene ID: ENSMUSG00000039219
  
Biological name :Arid4b
  
Synonyms : A2CG63 / Arid4b / AT-rich interactive domain-containing protein 4B
  
Possible biological names infered from orthology : AT-rich interaction domain 4B / Q4LE39
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A1
Gene start: 14063232
Gene end: 14199603
  
Corresponding Affymetrix probe sets: 10403680 (MoGene1.0st)   1431024_a_at (Mouse Genome 430 2.0 Array)   1431031_at (Mouse Genome 430 2.0 Array)   1435768_at (Mouse Genome 430 2.0 Array)   1446317_at (Mouse Genome 430 2.0 Array)   1451847_s_at (Mouse Genome 430 2.0 Array)   1460384_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106165
Ensembl peptide - ENSMUSP00000118687
Ensembl peptide - ENSMUSP00000152798
Ensembl peptide - ENSMUSP00000152177
Ensembl peptide - ENSMUSP00000043889
Ensembl peptide - ENSMUSP00000106162
Ensembl peptide - ENSMUSP00000106163
NCBI entrez gene - 94246     See in Manteia.
MGI - MGI:2137512
RefSeq - XM_006516806
RefSeq - XM_006516808
RefSeq - XM_017315648
RefSeq - NM_194262
RefSeq - NM_198122
RefSeq - XM_006516807
RefSeq Peptide - NP_937755
RefSeq Peptide - NP_919238
swissprot - Z4YMH1
swissprot - A0A1Y7VKA9
swissprot - A0A1Y7VIX3
swissprot - Z4YL44
swissprot - A2CG63
Ensembl - ENSMUSG00000039219
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tomm20aENSDARG00000090656Danio rerio
 ARID4BENSGALG00000034003Gallus gallus
 ARID4BENSG00000054267Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arid4a / AT rich interactive domain 4A (RBP1-like) / P29374* / AT-rich interaction domain 4A*ENSMUSG0000004811842
Arid5b / Q8BM75 / AT-rich interactive domain-containing protein 5B / Q14865* / AT-rich interaction domain 5B*ENSMUSG0000001994712
Arid5a / Q3U108 / AT-rich interactive domain-containing protein 5A / Q03989* / AT-rich interaction domain 5A*ENSMUSG000000374479


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR001606  ARID DNA-binding domain
 IPR002999  Tudor domain
 IPR012603  RBB1NT
 IPR016197  Chromo-like domain superfamily
 IPR025995  RNA binding activity-knot of a chromodomain
 IPR028853  AT-rich interactive domain-containing protein 4B
 IPR036431  ARID DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007283 spermatogenesis IGI
 biological_processGO:0034773 histone H4-K20 trimethylation IGI
 biological_processGO:0036124 histone H3-K9 trimethylation IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0097368 establishment of Sertoli cell barrier IGI
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000218 increased WBC count "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000240 extramedullary hematopoiesis "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000530 abnormal kidney vasculature "malformation or malfunctioning of the blood vessel network of the organ of excretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001750 increased circulating follicle stimulating hormone level "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001751 increased circulating luteinizing hormone level "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002026 leukemia "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002032 sarcoma "connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Raf1tm3Ulb/Raf1tm3Ulb
Genetic Background: Not Specified

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002397 abnormal bone marrow morphology "structural anomalies in the soft tissue that fills the cavities of bones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002414 abnormal myeloblast morphology/development "anomalous structure, formation, or numbers of the cells found in the bone marrow that give rise to the granulocyte line of blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003121 genomic imprinting "phenotype resulting from inactivation of specific loci during gametogenesis, but not encoded by the DNA itself" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003122 maternal imprinting "specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003131 increased erythrocyte count "greater number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003787 abnormal imprinting "defect in the normal inactivation of specific loci during gametogenesis" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Arid4btm1Alb/Arid4b+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004109 abnormal Sertoli cell development "anomalous differentiation of cells that support germ cell differentiation in males" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004809 increased hematopoietic stem cell number "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004884 abnormal testicular physiology "anomaly or loss either the production of male germ cells or the endocrine cells for the production testosterone" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004930 small epididymis "decrease in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005015 increased T cell number "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005460 abnormal leukopoiesis "anomalous process of generating white blood cells (leukocytes) from the pluripotent hematopoietic stem cells of the bone marrow; two significant pathways generate various types of leukocytes: myelopoiesis, in which leukocytes in the blood are derived from myeloid stem cells, and lymphopoiesis, in which leukocytes of the lymphatic system (lymphocytes) are generated from lymphoid stem cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0006378 abnormal spermatogonia morphology "anomaly in the number, structure or development of the large unspecialized male germ cells that give rise to spermatocytes" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006410 abnormal common myeloid progenitor cell morphology "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008877 abnormal DNA methylation "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]
Show

Allelic Composition: Arid4btm1Alb/Arid4b+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008878 abnormal DNA methylation during gametogenesis "any anomaly of the covalent transfer of a methyl group to C-5 of cytosine during gamete generation, when DNA methylation patterns are established" [GO:0043046]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Arid4btm1Alb/Arid4b+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009257 dilated seminiferous tubules "the luminal space of the seminiferous tubules is increased in volume or area, usually with an increase in contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0011750 abnormal seminiferous tubule epithelium morphology "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0013601 increased testis apoptosis "increase in the number of cells of the male reproductive glands undergoing programmed cell death" [MGI:Anna]
Show

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr