ENSG00000175866


Homo sapiens

Features
Gene ID: ENSG00000175866
  
Biological name :BAIAP2
  
Synonyms : BAI1 associated protein 2 / BAIAP2 / Q9UQB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.3
Gene start: 81035122
Gene end: 81117432
  
Corresponding Affymetrix probe sets: 205293_x_at (Human Genome U133 Plus 2.0 Array)   205294_at (Human Genome U133 Plus 2.0 Array)   207832_at (Human Genome U133 Plus 2.0 Array)   209502_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461144
Ensembl peptide - ENSP00000461101
Ensembl peptide - ENSP00000461736
Ensembl peptide - ENSP00000315685
Ensembl peptide - ENSP00000316338
Ensembl peptide - ENSP00000391837
Ensembl peptide - ENSP00000401022
Ensembl peptide - ENSP00000413069
Ensembl peptide - ENSP00000458202
Ensembl peptide - ENSP00000458440
Ensembl peptide - ENSP00000458494
Ensembl peptide - ENSP00000458522
Ensembl peptide - ENSP00000458735
Ensembl peptide - ENSP00000458964
Ensembl peptide - ENSP00000459730
Ensembl peptide - ENSP00000459787
Ensembl peptide - ENSP00000460131
Ensembl peptide - ENSP00000460344
Ensembl peptide - ENSP00000460350
Ensembl peptide - ENSP00000460492
NCBI entrez gene - 10458     See in Manteia.
OMIM - 605475
RefSeq - XM_017024019
RefSeq - NM_001144888
RefSeq - NM_006340
RefSeq - NM_017450
RefSeq - NM_017451
RefSeq - XM_005256943
RefSeq - XM_005256944
RefSeq - XM_005256945
RefSeq - XM_005256948
RefSeq - XM_006721635
RefSeq - XM_006721636
RefSeq - XM_006721637
RefSeq - XM_011524193
RefSeq - XM_011524194
RefSeq - XM_011524195
RefSeq - XM_011524196
RefSeq - XM_011524197
RefSeq - XM_017024017
RefSeq - XM_017024018
RefSeq Peptide - NP_059344
RefSeq Peptide - NP_059345
RefSeq Peptide - NP_006331
RefSeq Peptide - NP_001138360
swissprot - I3L125
swissprot - I3L1C8
swissprot - I3L2J6
swissprot - I3L2M4
swissprot - I3L327
swissprot - I3L3C5
swissprot - I3L3C6
swissprot - I3L3J7
swissprot - I3L4A3
swissprot - I3L4C2
swissprot - I3L526
swissprot - Q9UQB8
swissprot - B4DWA1
swissprot - I3L0M4
swissprot - I3L0Y9
swissprot - I3L113
Ensembl - ENSG00000175866
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 baiap2aENSDARG00000062799Danio rerio
 BAIAP2ENSGALG00000042538Gallus gallus
 Baiap2ENSMUSG00000025372Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UHR4 / BAIAP2L1 / BAI1 associated protein 2 like 1ENSG0000000645336
Q6UXY1 / BAIAP2L2 / BAI1 associated protein 2 like 2ENSG0000012829824


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR013606  IMD/I-BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR027681  I-BAR domain containing protein IRSp53/IRTKS/Pinkbar
 IPR030128  I-BAR domain containing protein IRSp53
 IPR035594  IRSp53, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007009 plasma membrane organization IEA
 biological_processGO:0007409 axonogenesis TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0016358 dendrite development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035418 protein localization to synapse IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway TAS
 biological_processGO:0048167 regulation of synaptic plasticity IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051764 actin crosslink formation IEA
 biological_processGO:0061003 positive regulation of dendritic spine morphogenesis IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1905232 cellular response to L-glutamate IEA
 biological_processGO:2000251 positive regulation of actin cytoskeleton reorganization IBA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043197 dendritic spine IEA
 cellular_componentGO:0043198 dendritic shaft IEA
 cellular_componentGO:0044306 neuron projection terminus IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 cellular_componentGO:0061845 neuron projection branch point IEA
 cellular_componentGO:0061846 dendritic spine cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097060 synaptic membrane IEA
 cellular_componentGO:0098793 presynapse IEA
 cellular_componentGO:0098794 postsynapse IEA
 molecular_functionGO:0001221 transcription cofactor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008022 protein C-terminus binding TAS
 molecular_functionGO:0008093 cytoskeletal adaptor activity IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0070064 proline-rich region binding IDA
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100030 MAPK1 / P28482 / mitogen-activated protein kinase 1  / reaction
 ENSG00000102882 MAPK3 / P27361 / mitogen-activated protein kinase 3  / reaction
 ENSG00000097007 ABL1 / P00519 / ABL proto-oncogene 1, non-receptor tyrosine kinase  / reaction
 ENSG00000075624 ACTB / P60709 / actin beta  / complex / reaction
 ENSG00000136238 RAC1 / P63000 / Rac family small GTPase 1  / complex / reaction
 ENSG00000184009 ACTG1 / P63261 / actin gamma 1  / reaction / complex






 

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