ENSG00000182175


Homo sapiens

Features
Gene ID: ENSG00000182175
  
Biological name :RGMA
  
Synonyms : Q96B86 / repulsive guidance molecule BMP co-receptor a / RGMA
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q26.1
Gene start: 93035273
Gene end: 93089204
  
Corresponding Affymetrix probe sets: 223468_s_at (Human Genome U133 Plus 2.0 Array)   234406_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452350
Ensembl peptide - ENSP00000440025
Ensembl peptide - ENSP00000404442
Ensembl peptide - ENSP00000330005
Ensembl peptide - ENSP00000452126
Ensembl peptide - ENSP00000452170
Ensembl peptide - ENSP00000456290
Ensembl peptide - ENSP00000442498
Ensembl peptide - ENSP00000451505
Ensembl peptide - ENSP00000451709
NCBI entrez gene - 56963     See in Manteia.
OMIM - 607362
RefSeq - NM_020211
RefSeq - NM_001166283
RefSeq - NM_001166286
RefSeq - NM_001166287
RefSeq - NM_001166288
RefSeq - NM_001166289
RefSeq Peptide - NP_001159755
RefSeq Peptide - NP_064596
RefSeq Peptide - NP_001159761
RefSeq Peptide - NP_001159760
RefSeq Peptide - NP_001159759
RefSeq Peptide - NP_001159758
swissprot - Q96B86
swissprot - A0A0A0MTQ4
swissprot - A0A0G2JL92
swissprot - F5H7G2
swissprot - G3V3Z3
swissprot - G3V4C2
swissprot - G3V545
Ensembl - ENSG00000182175
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rgmaENSDARG00000012248Danio rerio
 RGMAENSGALG00000039173Gallus gallus
 RgmaENSMUSG00000070509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RGMB / Q6NW40 / repulsive guidance molecule BMP co-receptor bENSG0000017413647
HFE2 / Q6ZVN8 / hemochromatosis type 2 (juvenile)ENSG0000016850943


Protein motifs (from Interpro)
Interpro ID Name
 IPR009496  Repulsive guidance molecule, C-terminal
 IPR010536  Repulsive guidance molecule, N-terminal
 IPR016123  Mog1/PsbP, alpha/beta/alpha sandwich
 IPR033607  Repulsive guidance molecule A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0010975 regulation of neuron projection development IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0030510 regulation of BMP signaling pathway IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048671 negative regulation of collateral sprouting IEA
 biological_processGO:0048681 negative regulation of axon regeneration IEA
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis IEA
 biological_processGO:1900121 negative regulation of receptor binding IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015026 coreceptor activity IBA
 molecular_functionGO:1990459 transferrin receptor binding IPI


Pathways (from Reactome)
Pathway description
Netrin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067141 NEO1 / Q92859 / neogenin 1  / complex / reaction






 

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