ENSG00000067141


Homo sapiens

Features
Gene ID: ENSG00000067141
  
Biological name :NEO1
  
Synonyms : NEO1 / neogenin 1 / Q92859
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q24.1
Gene start: 73051710
Gene end: 73305206
  
Corresponding Affymetrix probe sets: 204321_at (Human Genome U133 Plus 2.0 Array)   225270_at (Human Genome U133 Plus 2.0 Array)   229877_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453317
Ensembl peptide - ENSP00000261908
Ensembl peptide - ENSP00000341198
Ensembl peptide - ENSP00000454024
Ensembl peptide - ENSP00000453200
NCBI entrez gene - 4756     See in Manteia.
OMIM - 601907
RefSeq - XM_017022238
RefSeq - NM_001172623
RefSeq - NM_001172624
RefSeq - NM_002499
RefSeq - XM_017022233
RefSeq - XM_017022234
RefSeq - XM_017022235
RefSeq - XM_017022236
RefSeq - XM_017022237
RefSeq - XM_005254408
RefSeq - XM_011521628
RefSeq - XM_011521629
RefSeq - XM_011521630
RefSeq - XM_011521632
RefSeq - XM_011521633
RefSeq - XM_017022231
RefSeq - XM_017022232
RefSeq Peptide - NP_001166095
RefSeq Peptide - NP_002490
RefSeq Peptide - NP_001166094
swissprot - Q59FP8
swissprot - Q92859
Ensembl - ENSG00000067141
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neo1aENSDARG00000102855Danio rerio
 neo1bENSDARG00000075100Danio rerio
 NEO1ENSGALG00000001774Gallus gallus
 Neo1ENSMUSG00000032340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DCC / P43146 / DCC netrin 1 receptorENSG0000018732351
SDK1 / Q7Z5N4 / sidekick cell adhesion molecule 1ENSG0000014655523
SDK2 / Q58EX2 / sidekick cell adhesion molecule 2ENSG0000006918823
Q8TD84 / DSCAML1 / DS cell adhesion molecule like 1ENSG0000017710321
IGDCC4 / Q8TDY8 / immunoglobulin superfamily DCC subclass member 4ENSG0000010374221
DSCAM / O60469 / DS cell adhesion moleculeENSG0000017158720
PRTG / Q2VWP7 / protogeninENSG0000016645020
IGDCC3 / Q8IVU1 / immunoglobulin superfamily DCC subclass member 3ENSG0000017449815


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR010560  Neogenin, C-terminal
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR033024  Neogenin
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0055072 iron ion homeostasis IGI
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098797 plasma membrane protein complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0039706 co-receptor binding IPI


Pathways (from Reactome)
Pathway description
Netrin-1 signaling
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000065320 NTN1 / O95631 / netrin 1  / reaction / complex
 ENSG00000064309 CDON / Q4KMG0 / cell adhesion associated, oncogene regulated  / reaction / complex
 ENSG00000162068 NTN3 / O00634 / netrin 3  / complex
 ENSG00000145555 MYO10 / Q9HD67 / myosin X  / complex / reaction
 ENSG00000144857 BOC / Q9BWV1 / BOC cell adhesion associated, oncogene regulated  / reaction / complex
 ENSG00000174136 RGMB / Q6NW40 / repulsive guidance molecule BMP co-receptor b  / reaction / complex
 ENSG00000182175 RGMA / Q96B86 / repulsive guidance molecule BMP co-receptor a  / reaction / complex
 ENSG00000168509 HFE2 / Q6ZVN8 / hemochromatosis type 2 (juvenile)  / reaction / complex






 

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