ENSG00000162068


Homo sapiens

Features
Gene ID: ENSG00000162068
  
Biological name :NTN3
  
Synonyms : netrin 3 / NTN3 / O00634
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2471499
Gene end: 2474145
  
Corresponding Affymetrix probe sets: 207640_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293973
NCBI entrez gene - 4917     See in Manteia.
OMIM - 602349
RefSeq - NM_006181
RefSeq Peptide - NP_006172
swissprot - O00634
Ensembl - ENSG00000162068
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ntn2ENSDARG00000076748Danio rerio
 NTN3ENSGALG00000029072Gallus gallus
 Q3UUG6ENSMUSG00000036473Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NTN1 / O95631 / netrin 1ENSG0000006532054
NTN5 / Q8WTR8 / netrin 5ENSG0000014223337
USH2A / O75445 / usherinENSG0000004278126
NTNG2 / Q96CW9 / netrin G2ENSG0000019635826
NTNG1 / Q9Y2I2 / netrin G1ENSG0000016263125
MEGF9 / Q9H1U4 / multiple EGF like domains 9ENSG0000010678014


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR002049  Laminin EGF domain
 IPR008211  Laminin, N-terminal
 IPR008979  Galactose-binding-like domain superfamily
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR018933  Netrin module, non-TIMP type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007411 axon guidance NAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000064309 CDON / Q4KMG0 / cell adhesion associated, oncogene regulated  / complex / reaction
 ENSG00000067141 NEO1 / Q92859 / neogenin 1  / complex
 ENSG00000144857 BOC / Q9BWV1 / BOC cell adhesion associated, oncogene regulated  / complex / reaction






 

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contact: otassy@igbmc.fr