ENSG00000069188


Homo sapiens

Features
Gene ID: ENSG00000069188
  
Biological name :SDK2
  
Synonyms : Q58EX2 / SDK2 / sidekick cell adhesion molecule 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 73334384
Gene end: 73644089
  
Corresponding Affymetrix probe sets: 220628_s_at (Human Genome U133 Plus 2.0 Array)   232061_at (Human Genome U133 Plus 2.0 Array)   233585_at (Human Genome U133 Plus 2.0 Array)   234073_at (Human Genome U133 Plus 2.0 Array)   242064_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376421
Ensembl peptide - ENSP00000407098
NCBI entrez gene - 54549     See in Manteia.
OMIM - 607217
RefSeq - XM_011524915
RefSeq - NM_001144952
RefSeq - XM_011524914
RefSeq Peptide - NP_001138424
swissprot - Q58EX2
swissprot - H7C2P2
Ensembl - ENSG00000069188
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sdk2bENSDARG00000060452Danio rerio
 si:ch211-148f13.1ENSDARG00000102161Danio rerio
 SDK2ENSGALG00000031895Gallus gallus
 Sdk2ENSMUSG00000041592Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SDK1 / Q7Z5N4 / sidekick cell adhesion molecule 1ENSG0000014655559
DSCAM / O60469 / DS cell adhesion moleculeENSG0000017158717
DCC / P43146 / DCC netrin 1 receptorENSG0000018732316
Q8TD84 / DSCAML1 / DS cell adhesion molecule like 1ENSG0000017710316
NEO1 / Q92859 / neogenin 1ENSG0000006714115
IGDCC4 / Q8TDY8 / immunoglobulin superfamily DCC subclass member 4ENSG0000010374213
PRTG / Q2VWP7 / protogeninENSG0000016645011
IGDCC3 / Q8IVU1 / immunoglobulin superfamily DCC subclass member 3ENSG000001744989


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0010842 retina layer formation IEA
 biological_processGO:0045216 cell-cell junction organization TAS
 biological_processGO:0060219 camera-type eye photoreceptor cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse ISS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
SDK interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069188 SDK2 / Q58EX2 / sidekick cell adhesion molecule 2  / reaction / complex






 

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contact: otassy@igbmc.fr