ENSMUSG00000041592


Mus musculus

Features
Gene ID: ENSMUSG00000041592
  
Biological name :Sdk2
  
Synonyms : Protein sidekick-2 / Q6V4S5 / Sdk2
  
Possible biological names infered from orthology : Q58EX2 / sidekick cell adhesion molecule 2
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 113776374
Gene end: 114067046
  
Corresponding Affymetrix probe sets: 10392739 (MoGene1.0st)   1430425_at (Mouse Genome 430 2.0 Array)   1457333_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038972
Ensembl peptide - ENSMUSP00000116872
NCBI entrez gene - 237979     See in Manteia.
MGI - MGI:2443847
RefSeq - XM_006533255
RefSeq - NM_172800
RefSeq - XM_006533253
RefSeq - XM_006533254
RefSeq Peptide - NP_766388
swissprot - B1ASR7
swissprot - Q6V4S5
Ensembl - ENSMUSG00000041592
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sdk2bENSDARG00000060452Danio rerio
 si:ch211-148f13.1ENSDARG00000102161Danio rerio
 SDK2ENSGALG00000031895Gallus gallus
 SDK2ENSG00000069188Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sdk1 / Q3UH53 / Protein sidekick-1 / Q7Z5N4* / sidekick cell adhesion molecule 1*ENSMUSG0000003968358
Dscam / Q9ERC8 / Down syndrome cell adhesion molecule homolog / O60469* / DS cell adhesion molecule*ENSMUSG0000005027217
Dcc / P70211 / Netrin receptor DCC / P43146* / DCC netrin 1 receptor*ENSMUSG0000006053416
Dscaml1 / DS cell adhesion molecule like 1 / Q8TD84*ENSMUSG0000003208716
Neo1 / neogenin / Q92859* / neogenin 1*ENSMUSG0000003234015
Igdcc4 / Q9EQS9 / Immunoglobulin superfamily DCC subclass member 4 / Q8TDY8*ENSMUSG0000003281613
Prtg / Q2EY15 / Protogenin / Q2VWP7*ENSMUSG0000003603011
Igdcc3 / Q8BQC3 / Immunoglobulin superfamily DCC subclass member 3 / Q8IVU1*ENSMUSG000000323948


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IDA
 biological_processGO:0007416 synapse assembly ISS
 biological_processGO:0010842 retina layer formation ISS
 biological_processGO:0060219 camera-type eye photoreceptor cell differentiation IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
SDK interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Tsc1tm1Djk/Tsc1tm1Djk,Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor

Allelic Composition: Gt(ROSA)26Sortm1.1(CAG-Venus,-Sdk2)Jrs/Gt(ROSA)26Sor+,Sdk2tm1.1(cre/ERT2)Jrs/Sdk2tm1.1(cre/ERT2)Jrs
Genetic Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000041592 Sdk2 / Q6V4S5 / Protein sidekick-2 / Q58EX2* / sidekick cell adhesion molecule 2*  / complex / reaction






 

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