ENSG00000182263


Homo sapiens

Features
Gene ID: ENSG00000182263
  
Biological name :FIGN
  
Synonyms : fidgetin, microtubule severing factor / FIGN / Q5HY92
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q24.3
Gene start: 163593396
Gene end: 163736012
  
Corresponding Affymetrix probe sets: 222956_at (Human Genome U133 Plus 2.0 Array)   238964_at (Human Genome U133 Plus 2.0 Array)   239710_at (Human Genome U133 Plus 2.0 Array)   242828_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333836
Ensembl peptide - ENSP00000386768
NCBI entrez gene - 55137     See in Manteia.
OMIM - 605295
RefSeq - NM_018086
RefSeq - XM_011511389
RefSeq Peptide - NP_060556
swissprot - B8ZZS6
swissprot - Q5HY92
Ensembl - ENSG00000182263
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fignENSDARG00000008662Danio rerio
 FIGNENSGALG00000011069Gallus gallus
 FignENSMUSG00000075324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NMB9 / FIGNL2 / fidgetin like 2ENSG0000026130836
FIGNL1 / Q6PIW4 / fidgetin like 1ENSG0000013243635
SPAST / Q9UBP0 / spastinENSG0000002157420
IQCA1 / Q86XH1 / IQ motif containing with AAA domain 1ENSG0000013232114
IQCA1L / IQ motif containing with AAA domain 1 likeENSG0000027868514


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IBA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016363 nuclear matrix ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0016887 ATPase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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